代谢病药理学与新药发现
职 称:研究员
所属科室:国家药物筛选中心
导师类别:博士生导师
联系方式:010-63165313
所属重点实验室:脑血管病新药发现及晶型研究北京市重点实验室
1. Hou B#, Ma P#, Yang X#, Zhao X, Zhang L, Zhao Y, He P, Zhang L, Du G*, Qiang G*. In silico prediction and experimental validation to reveal the protective mechanism of Puerarin against excessive extracellular matrix accumulation through inhibiting ferroptosis in diabetic nephropathy. J Ethnopharmacol. 2024;319(Pt 2):117281.
2. Xu T#, He P#, namWangdu S#, Xu C, Hou B, Ma P, Wang Z, Zhang L, Du G, Ring T*, Ji T*, Qiang G*. Revealing the improvement of diabetes by Si Wei Jiang Huang Tang San through ERK/HIF1α signaling pathway via network pharmacology. J Ethnopharmacol. 2024;319(Pt 2):117254.
3. Wang ZJ, Ma P, Xu CY, Xu TS, Zhang L, He P, Hou BY, Yang XY, Du GH, Ji TF*, Qiang GF*. Identification of a novel hypoglycemic small molecule, trans-2, 4-dimethoxystilbene by rectifying gut microbiota and activating hepatic AMPKα-PPARγ pathway through gut-liver axis. Biomed Pharmacother. 2024;176:116760.
4. Ma P, Xiao J, Hou B, He P, Yang X, Wang Y, Wang Z, Xu T, Yang X, Zhu X, Xiang S, Li S, Du G*, Ying J*, Qiang G*. Carbonic anhydrase 2 mediates anti-obesity effects of black tea as thermogenic activator. Food Sci Hum Well. 2024, 13(5):2917-2936.
5. Wang Y#, Ma P#, Wang Z, Sun M, Hou B, Xu T, Li W, Yang X, Du G, Ji T*, Qiang G*. Uncovering the effect and mechanism of Panax notoginseng saponins on metabolic syndrome by network pharmacology strategy. J Ethnopharmacol. 2023;300:115680.
6.Li N, Yin L, Shang J, Liang M, Liu Z, Yang H, Qiang G*, Du G, Yang X*. Kaempferol attenuates nonalcoholic fatty liver disease in type 2 diabetic mice via the Sirt1/AMPK signaling pathway. Biomed Pharmacother. 2023;165:115113.