1. 智能药物输送系统的研究
2. 生物大分子递送系统的研究
3. 肿瘤联合免疫治疗

1. Liu D, Liang S, Ma K, Meng Q, Li X, Wei J, Zhou M, Yun K, Pan Y, Rao L*, Chen X*, Wang Z*. Tumor Microenvironment-Responsive Nanoparticles Amplifying STING Signaling Pathway for Cancer Immunotherapy. Advanced Materials 2024, 2304845.
2. Peng Y, Liang S, Meng Q, Liu D, Ma K, Zhou M, Yun K, Rao L*, Wang Z*. Engineered Bio-Based Hydrogels for Cancer Immunotherapy. Advanced Materials 2024, 2313188.
3. Peng Y, Liang S, Liu D, Ma K, Yun K, Zhou M, Hai L, Xu M, Chen Y, Wang Z*. Multi-Metallic Nanosheets Reshaping Immunosuppressive Tumor Microenvironment through Augmenting cGAS-STING Innate Activation and Adaptive Immune Responses for Cancer Immunotherapy. Advanced Science 2024, 2403347.
4. Liu Dan, Liang S, Ma K, Yun K, Zhou M, Yao J, Hai L, Peng Y, Wang Z*. A bi-adjuvant nanovaccine amplifying STING activation for cancer immunotherapy. Nano Today 2024, 102372.
5. Liang S, Yao J, Liu D, Zhou M, Cui Y*, Wang Z*. Tumor-responsive covalent organic polymeric nanoparticles enhancing STING activation for cancer immunotherapy. Chinese Chemical Letters 2024, 109856.
6. Liang S, Ma M, Li X, Yun K, Meng Q, Ma K, Liu D, Yue L, Rao L*, Chen X*, Wang Z*. A Guanidinobenzol-Rich Polymer Overcoming Cascade Delivery Barriers for CRISPR-Cas9 Genome Editing. Nano Letters 2024. 24, 6872-6880.（Front Cover）
7. Pan Y, Liu L, Zhang J, Liang S, Parshad B, Lai J, Ma L, Wang Z*, Rao L*. Genetically Engineered Nanomodulators Elicit Potent Immunity against Cancer Stem Cells by Checkpoint Blockade and Hypoxia Relief. Bioactive Materials 2024, 38, 31-44.
8. Liang S, Yao J, Liu D, Rao L*, Chen X*, Wang Z*. Harnessing Nanomaterials for Cancer Sonodynamic Immunotherapy. Advanced Materials. 2023, 2211130.
9. Zhou M, Liang S, Liu D, Ma K, Yun K, Yao J, Peng Y, Hai L, Zhang Q*, Wang Z*. Manganese-enriched Zinc Peroxide Functional Nanoparticles for Potentiating Cancer Immunotherapy. Nano Letters. 2023, 23, 22, 10350–10359.
10. Zhou M, Liang S, Liu D, Ma K, Peng Y, Wang Z*. Engineered Nanoprobes for Immune Activation Monitoring. ACS Nano. 2022, 16, 19940-19958.
11. Luo M*, Wang H*, Wang Z*, et al. A STING-activating nanovaccine for cancer immunotherapy. Nature Nanotechnology. 2017, 12, 648-654. (*Co-first author, Equal contribution).
12. Wang Z*, Luo M*, Mao C, et al. A redox-activatable fluorescent sensor for the high-throughput quantification of cytosolic delivery of macromolecules. Angewandte Chemie International Edition. 2017, 129, 1339-1343.
13. Aroh C*, Wang Z*, Dobbs N, et al. Innate immune activation by cGAMP-PC7A nanoparticles leads to potent and long-acting antiretroviral response against HIV-1. Journal of Immunology. 2017, 199, 3840-3848. (*Co-first author)
14. Wang Z, Yu Y, Dai W, et al. A specific peptide ligand-modified lipid nanoparticle carrier for the inhibition of tumor metastasis growth. Biomaterials. 2013, 34, 756-764.
15. Wang Z, Yu Y, Ma J, et al. LyP-1 modification to enhance delivery of artemisinin or fluorescent probe loaded polymeric micelles to highly metastatic tumor and its lymphatics. Molecular Pharmaceutics. 2012, 9, 2646-2657.
16. Wang Z, Yu Y, Dai W, et al. The use of a tumor metastasis targeting peptide to deliver doxorubicin-containing liposomes to highly metastatic cancer. Biomaterials. 2012, 33, 8451-8460.
17. Wang Z, Wang Z, Sun C, et al. Trimethylated chitosan-conjugated PLGA nanoparticles for the delivery of drugs to the brain. Biomaterials. 2010, 31, 908-915.