主要从事药剂学研究工作，研究方向为纳米递送系统研究。主持过国家自然科学基金青年基金和协和医学院研究生创新基金；参与过“重大新药创制”国家科技重大专项基金、国家自然科学基金等项目、北京市自然基金项目等10多项研究。工作期间主要从事了生物大分子药物、难溶性药物、抗肿瘤基因药物及化疗药物的递送研究，口服结肠癌定位给药系统的研究，光动力疗法以及免疫疗法对肿瘤的治疗等多方面研究。期间发表了SCI论文35篇，核心期刊论文11篇，申请发明专利6项，获授权专利3项。从2020年开始参与《综合临床药物治疗学》课程的教学工作，并协助课题组长培养多名博士生和研究生。2014年11月曾获吉林省科学技术奖二等奖。

1. 小分子抗肿瘤化疗药纳米靶向制剂的研究
2. 基因药物递送系统的研究
3. 生物大分子药物的递送研究
4. 光动力疗法对肿瘤的治疗
5. 抗肿瘤免疫疗法的研究

[1] Biomimetic multifunctional nanodrugs enable regulating abnormal tumor metabolism and amplifying PDT-induced immunotherapy for synergistically enhanced tumor ablation. Yanhong Liu, Hao Wu, Shuangqing Wang, Xintong Zhang, Liming Gong, Congcong Xiao, Chenfei Liu, Liqing Chen, Heming Zhao, Chao Liu, Minji Jin, Zhonggao Gao*, Wei Huang*, Materials today, 2023, 68:125-147
[2] Versatile flexible micelles integrating mucosal penetration and intestinal targeting for effectively oral delivery of paclitaxel. Chao Liu, Wei Liu, Yanhong Liua, Hongxia Duana, Liqing Chen, Xintong Zhang, Mingji Jin, Minhu Cui, Xiuquan Quan, Libin Pan, Jiachun Hu, Zhonggao Gaoa*, Yan Wang*, Wei Huang*. Acta Pharmaceutica Sinica B, 2023;13(8):3425-3443
[3] An EGCG-mediated self-assembled micellar complex acts as a bioactive drug carrier. Chao Liu, Hao Wu, Hongxia Duan, Yan Hou, Shuangqing Wang, Yanhong Liu, Xintong Zhang, Heming Zhao, Liming Gong, Hongshuang Wan, Bowen Zeng, Xiuquan Quan, Minhu Cui, Liqing Chen, Mingji Jin, Qiming Wang, Zhonggao Gao*, Wei Huang*. Food Chemistry, 2023, 418: 135939
[4] Combined Biomimetic MOF-RVG15 Nanoformulation Efficient Over BBB for Effective Anti-Glioblastoma in Mice Model. Hao Wu, Yanhong Liu, Liqing Chen, Shuangqing Wang, Chao Liu, Heming Zhao, Mingji Jin, Shuangyan Chang, Xiuquan Quan, Minhu Cui, Hongshuang Wan, Zhonggao Gao*, Wei Huang*, International Journal of Nanomedicine, 2022:17, 6377–6398
[5] Targeted therapeutic effects of oral inulin-modifed double-layered nanoparticles containing chemotherapeutics on orthotopic colon cancer. Yan Hou, Jingzhe Jin, Hongxia Duan, Chao Liu, Liqing Chen, Wei Huang, Zhonggao Gao, Mingji Jin*, Biomaterials, 2022, 283:121440
[6] Co-delivery of repurposing Itraconazole and VEGF siRNA by composite nanoparticulate system for collaborative anti-angiogenesis and anti-tumor efficacy against breast cancer. Mingji Jin, Bowen Zeng, Yanhong Liu, Lili Jin, Yan Hou, Chao Liu, Wei Liu, Hao Wu, Liqing Chen, Zhonggao Gao*, Wei Huang*. Pharmaceutics, 2022, 14(7): 1369.
[7] Biomimetic and temporal-controlled nanocarriers with ileum transporter targeting for achieving oral administration of chemotherapeutic drugs. Wei Liu, Ying Han, Xin xin, Liqing Chen, Yanhong Liu, Chao Liu, Xintong Zhang, Mingji Jin, Jingzhe Jin, Zhonggao Gao, Wei Huang, Journal of Nanobiotechnology, 2022, 20:281
[8] Sequential Delivery of Quercetin and Paclitaxel for the Fibrotic Tumor Microenvironment Remodeling and Chemotherapy Potentiation via a Dual-Targeting Hybrid Micelle-in-Liposome System. Hongxia Duan, Chao Liu, Yan Hou, Yanhong Liu, Zheao Zhang, Heming Zhao, Xin Xin, Wei Liu, Xintong Zhang, Liqing Chen, Mingji Jin, Zhonggao Gao*, and Wei Huang*. ACS Appl. Mater. Interfaces 2022, 14, 10102−10116
[9] Smart polymeric nanoparticles with pH-responsive and PEG-detachable properties (Ⅱ): Co-delivery of paclitaxel and VEGF siRNA for synergistic breast cancer therapy in mice. Mingji Jin, Yan Hou, Xiuquan Quan, Liqing Chen, Zhonggao Gao, Wei Huang. International Journal of Nanomedicine, 2021, 16:5479-5494.
[10] Effective oral delivery of Exenatide-Zn2+ complex through distal ileum-targeted double layers nanocarriers modified with deoxycholic acid and glycocholic acid in diabetes therapy. Ying Han, Wei Liu, Liqing Chen, Xin Xin, Qiming Wang, Xintong Zhang, Mingji Jin, Zhonggao Gao*, Wei Huang*. Biomaterials, 2021, 275:120944
[11] Smart polymeric nanoparticles with pH-responsive and PEG-detachable properties for co-delivering paclitaxel and survivin siRNA to enhance antitumor outcomes. Mingji Jin, Guangming Jin, Lin Kang, Liqing Chen, Zhonggao Gao*, Wei Huang*. International Journal of Nanomedicine, 2018, 13: 2405-2426. (IF: 4.47)

Nanobiomaterials Handbook, Sitharaman, Balaji, CRC Press, 2011.

[1] 一种聚乙烯亚胺-b-聚乳酸嵌段共聚物、其制备方法及应用，高钟镐、金明姬、黄伟， CN109734921B
[2] 还原敏感性聚乙烯亚胺衍生物，其制备方法及应用，高钟镐,刘珊，黄伟, 杨飞飞，金明姬，CN104945629
[3] 一种巴氯芬微球制剂及其制备方法，高钟镐，黄伟，金明姬，李今子，金辉哲，金帅星，张进，CN103520117B
[4] 一种口服结肠靶向高分子聚合物的制备及应用，高钟镐，金明姬，侯妍，202210144847.1
[5] 一种紫杉烷类长循环纳米粒及其制备方法. 高钟镐，陈卫，金明姬，201410053890.2
[6] 脂肪烃基接枝的低分子量聚乙烯亚胺,制备方法及应用，高钟镐，柳珊，黄伟，杨飞飞，金明姬，201310244851.6

2014.11，长白山抗肝损伤代表性道地朝药万年蒿作用机理等系列研究，朴光春、元海丹、金光洙、李镐、李英姬、姜英子、吕惠子、金明姬。吉林省科学技术奖，二等奖。