1. CKLF induces microglial activation via triggering defective mitophagy and mitochondrial dysfunction. Wang H, Ye J, Peng Y, Ma W, Chen H, Sun H, Feng Z, He W, Li G, Chu S*, Zhang Z*, Chen N*. Autophagy. 2023 Oct 31. doi: 10.1080/15548627.2023.2276639.
2. A small molecule 20C from Gastrodia elata inhibits α-synuclein aggregation and prevents progression of Parkinson's disease. Peng Y, Ye JR, Wang SS, He WB, Feng ZP, Sun HS, Chu SF*, Zhang Z*, Chen NH*. Cell Death Dis. 2023 Sep 6;14(9):594.
3. A breakdown of metabolic reprogramming in microglia induced by CKLF1 exacerbates immune tolerance in ischemic stroke. Wen-Yu Ma, Qing-Lin Wu, Sha-Sha Wang, Hong-Yun Wang, Jun-Rui Ye, Hong-Shuo Sun, Zhong-Ping Feng, Wen-Bin He, Shi-Feng Chu*, Zhao Zhang*, Nai-Hong Chen* Journal of neuroinflammation. 2023;20(1):97.
4. A novel small-molecular CCR5 antagonist promotes neural repair after stroke. Wu QL, Cui LY, Ma WY, Wang SS, Zhang Z, Feng ZP, Sun HS, Chu SF*, He WB*, Chen NH*. Acta Pharmacol Sin. 2023 Oct;44(10):1935-1947.
5. Pyk2 inhibition attenuates hypoxic-ischemic brain injury in neonatal mice. Zhu J, Chu SF, Peng Y, Liu DD, Chen C, Jian WX, Sun HS, Feng ZP, Zhang Z*, Chen NH*. Acta Pharmacol Sin. 2022 April;43(4):797–810.
6. Rg1 exerts protective effect in CPZ-induced demyelination mouse model via inhibiting CXCL10-mediated glial response. Dong YX, Chu SF, Wang SS, Tian YJ, He WB, Du YS, Wang ZZ, Yan X, Zhang Z*, Chen NH*. Acta Pharmacol Sin. 2022 Mar;43(3):563-576.
7. Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours. Yu, X; Bai, Y; Han, B; Ju, M; Tang, T; Shen, L; Li, M; Yang, L; Zhang, Z; Hu, G; Chao, J; Zhang, Y; Yao, H, J Extracell Vesicles. 2022 Jan;11(1):e12185.
8. Low corticosterone levels attenuate late life depression and enhance glutamatergic neurotransmission in female rats. Shi-Feng Chu#, Zhao Zhang#, Xin Zhou, Wen-Bin He, Bo Yang, Li-Yuan Cui, Hong-Yuan He, Zhen-Zhen Wang, Nai-Hong Chen*. Acta Pharmacol Sin. 2021;42(6):848-860.
9. PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery. Tang, Y; Liu, J; Wang, Y; Yang, L; Han, B; Zhang, Y; Bai, Y; Shen, L; Li, M; Jiang, T; Ye, Q; Yu, X; Huang, R; Zhang, Z; Xu, Y; Yao, H, Autophagy, 2021, 17(10): 2905-2922
10. CZ-7, a new derivative of Claulansine F, promotes remyelination induced by cuprizone by enhancing myelin debris clearance. Wang SS#, Bi HZ, Chu SF, Dong YX, He WB, Tian YJ, Zang YD, Zhang DM, Zhang Z*, Chen NH*. Brain Res Bull. 2020 Jun;159:67-78.
11. A20 as a novel target for the anti-neuroinflammatory effect of chrysin via inhibition of NF-κB signaling pathway. Zhi-peng Li#, Shi-feng Chu#, Wen-bin He, Zhao Zhang, Jia-qi Liu, Li-yuan Cui, Xu Yan, De-fang Li, Nai-hong Chen*. Brain Behav Immun. 2019;79:228-235.
12. RTP801 is a critical factor in the neurodegeneration process of A53T α-synuclein in a mouse model of Parkinson's disease under chronic restraint stress. Zhao Zhang#, Shi-Feng Chu#, Sha-Sha Wang, Yi-Na Jiang, Yan Gao, Peng-Fei Yang, Qi-Di Ai, Nai-Hong Chen*. Br J Pharmacol. 2018;175(4):590-605.
13. Helioscopianoids A–Q, bioactive jatrophane diterpenoid esters from Euphorbia helioscopia. Mai ZP#, Ni G, Liu YF, Zhang Z, Li L, Chen NH, Yu DQ*. Acta Pharm Sin B. 2018 Sep;8(5):805-817.
14. Upregulating the Expression of Survivin-HBXIP Complex Contributes to the Protective Role of IMM-H004 in Transient Global Cerebral Ischemia/Reperfusion. Shi-Feng Chu#, Zhao Zhang#, Wei Zhang, Mei-Jin Zhang, Yan Gao, Ning Han, Wei Zuo, Hui-Yong Huang, Nai-Hong Chen*. Mol Neurobiol. 2017;54(1):524-540.
15. Ganglioside GQ1b induces dopamine release through the activation of Pyk2. Zhang Z#, Chu SF, Mou Z, Gao Y, Wang ZZ, Wei GN, Chen NH*.Mol Cell Neurosci. 2016 Mar;71:102-13.
16. The oncoprotein HBXIP enhances migration of breast cancer cells through increasing filopodia formation involving MEKK2/ERK1/2/Capn4 signaling. Li Y#, Zhang Z#, Zhou X, Li L, Liu Q, Wang Z, Bai X, Zhao Y, Shi H, Zhang X*, Ye L*. 2014. Cancer Lett. Dec 28;355 (2):288-96.
17. Tyrosine 402 phosphorylation of Pyk2 is involved in ionomycin-induced neurotransmitter release. Zhang, Z#, Zhang, Y., Mou, Z., Chu, S., Chen, X., He, W., Guo, X., Yuan, Y., Takahashi, M. (*), Chen, N. (*), 2014. PLoS One 9, e94574.