EN

科研队伍

您现在的位置: 首页> 科研队伍> 副研究员

副研究员

王玉红

职 称:副研究员

所属科室:药理学研究室

导师类别:硕士生导师

联系方式:wangyh@imm.ac.cn

所属重点实验室:

个人简介

1997-2008年分别获得河北医科大学临床医学专业学士学位、药理学硕士学位和生理学博士学位。2008年10月~2014年10月在美国弗吉尼亚联邦大学做博士后、任职。2014年12月加入中国医学科学院药物研究所药理室工作,于2017年聘为副研究员。主持国家自然科学基金1项。发表SCI论文21篇。

研究方向

心血管药理和分子药理

发表论文

1. Auxiliary subunits control biophysical properties and response tocompound NS5806 of the Kv4 potassium channel complex. Hongxue Zhang, Hua Zhang, Chanjuan Wang, Yuhong Wang, Ruya Zou, Chenxia Shi, Bingcai Guan, Nikita Gamper, Yanfang Xu. the FASEB Journal. 2020
2. The cajanine derivative LJ101019C regulates the proliferation and enhances the activity of NK cells via Kv1.3 channel-driven activation of the AKT/mTOR pathway. Jing Geng*, Yuhong Wang*, Lei Zhang, Ruiqi Wang, Cong Li, Weijin Sheng, Zhuorong Li, Min Jiang. Phytomedicine. 2020
3. Upregulation of phosphoinositide 3‑kinase prevents sunitinib‑induced cardiotoxicity in vitro and in vivo. Congxin Li, Ruya Zou, Hua Zhang, Yuhong Wang, Bo Qiu5, Suhua Qiu, Wei Wang, Yanfang Xu. Archives of Toxicology. 2019
4. The cardiac electrophysiology effects of higenamine in guinea pig heart. Biomed Pharmacother. Yuhong Wang, Jing Geng, MinJiang, CongLi,Yanxing Han, Jiandong Jiang. 2019.
5. Utility of the JT Peak Interval and the JT Area in Determining the Proarrhythmic Potential of QT-Shortening Agents. Bo Qiu, Yuhong Wang, Congxin Li, HuiCai Guo, Yanfang Xu. J Cardiovasc Pharmacol Ther. 2018 5.
6. Distinct protein kinase C isoenzyme mediates inhibitory effects of different G-protein coupled receptors on cardiac rapidly activating delayed rectifier K+ current. Xueli Liu*, Yuhong Wang*, Hua Zhang, Li Shen, Yanfang Xu. Br J Pharmacol. 2017.
7. Adult Ventricular Myocytes Segregate KCNQ1 and KCNE1 to Keep the IKs Amplitude in Check Until When Larger IKs Is Needed. Min Jiang, Yuhong Wang, Gea-Ny Tseng. Circ Arrhythm Electrophysiol. 2017.
8. JPH-2 interacts with Cai-handling proteins and ion channels in dyads: Contribution to premature ventricular contraction-induced cardiomyopathy. Min Jiang, Mei Zhang, Maureen Howren, Yuhong Wang, Alex Tan, Ravi C. Balijepalli, Jose F. Huizar, Gea-Ny Tseng*. Heart Rhythm. 2016
9. A Ligand-Based Virtual Screening Approach to Identify Small Molecules as hERG Channel Activators. lisa Giacomini, Rosa Buonfiglio, Matteo Masetti, Yuhong Wang, Gea-Ny Tseng, Marinella Roberti, and Maurizio Recanatini. Combinatorial Chemistry & High Throughput Screening. 2015
10. Probing Binding Sites and Mechanisms of Actions of and Iks Activation by Computations and Experiments. Yu Xu, Yuhong Wang, Mei Zhang, Min Jiang, Avia Rosenhouse-Dantsker, Tsjerk Wassenaar, and Gea-Ny Tseng. Biophys J. 2015
11. Cellular Mechanism of Premature Ventricular Contraction-induced Cardiomyopathy Yuhong Wang, Jose M. Eltit, Karoly Kaszala, Alex Tan, Min Jiang, Mei Zhang, Gea-Ny Tseng, Jose F. Huizar.. Heart rhythm. 2014
12. Down-regulation of Ether-a-go-go-Related Gene Potassium Channel Protein through Sustained Stimulation of AT1 Receptor by Angiotensin II. Yue Cai*, Yuhong Wang*, Jia Xu, Xu Zuo, Yanfang Xu. Biochem Biophys Res Commun. 2014

专著

专利

科技奖励