中国医学科学院药物研究所天然药药理学研究室副研究员。2005年本科毕业于清华大学生物系，2010年博士毕业于清华大学生命学院。2010-2014年以博士后身份在美国波士顿东北大学从事毒理学研究工作。2014年开始在药物研究所从事药理学研究工作。担任 Environmental Science & Technology，BMC Complementary and Alternative Medicine等期刊审稿人, 中国药理学会抗衰老与老年痴呆专业委员会第一届青年委员会常务委员和中国药理学会精神神经药理学专业委员会青年委员，主持国自然青年项目和开放实验室课题，并参与国家自然科学基金、重大新药创制国家科技重大专项和中国医学科学院与健康科技创新工程等项目。

主要从事神经精神药物的发现、开发和药理学研究，包括抗焦虑和抗抑郁药物的药效评价和药理学研究，神经退行性疾病（阿尔茨海默病、肌萎缩性侧索硬化症）新药发现与机制研究。

1. Antidepressant effect of 4-Butyl-a-agarofuran via HPA axis and serotonin system. Hongyue Wang, Jinping Hu, Jiahuan Hu, Qiuyu Chen, Nianying Shang, Mengyao Liu, Xinnan Li, Longgang Xiang, Dali Yin, Jiaqi Lan*, Qiong Xiao*, Ying Peng*.Brain Research Bulletin. 2023, 198:3-14
2. Protective effect of human umbilical cord mesenchymal stem cell derived conditioned medium in a mutant TDP-43 induced motoneuron-like cellular model of ALS. Jiaqi Lan, Yujun Zhou，Hongyue Wang, Jingshu Tang, Yuying Kang, Peishen Wang, Xuebin Liu*, Ying Peng*. 2023, 193:106-116
3. ALS-causing SOD1 mutants regulate occludin phosphorylation/ubiquitination and endocytic trafficking via the ITCH/Eps15/Rab5 axis. Jingshu Tang, Yuying Kang, Yujun Zhou, Xinnan Li, Jiaqi Lan, Lei Wu, Xinhong Feng*, Ying Peng*. Neurobiology of Disease. 2021, 153（2021）105315
4. Molecular mechanisms of mitophagy and its roles in neurodegenerative diseases. Xinnan Li, Longjian Huang, Jiaqi Lan, Xinhong Feng, Pingping Li, Lei Wu, Ying Peng*. Pharmacological Research. 2021
5. 抗焦虑障碍药物非临床药效学评价体系探索. 兰嘉琦，赵春阳，吴镭，冯新红，王庆利*，彭英*. 药学学报. 2021
6. L-3-n-Butylphthalide improves synaptic and dendritic spine plasticity and ameliorates neurite pathology in Alzheimer’s disease mouse model and cultured hippocampal neurons. Longjian Huang, Jiaqi Lan, Jingshu Tang, Yuying Kang, Xinhong Feng, Lei Wu, Ying Peng*. Molecular Neurobiology. 2020
7. The MMP-2/TIMP-2 system in Alzheimer disease. Hongyue Wang, Longjian Huang, Lei Wu ,Jiaqi Lan, Xinhong Feng, Pingping Li，Ying Peng*. CNS & Neurological Disorders-Drug Targets. 2020
8. Toxicity of single-walled carbon nanotubes (SWCNTs): effect of lengths, functional groups and electronic structures revealed by a quantitative toxicogenomics assay. Tao Jiang, Carlo Alberto Amadei, Na Gou, Yishan Lin, Jiaqi Lan*, Chad D. Vecits and April Z. Gu*. Environmental Science: Nano. 2020
9. 抗阿尔茨海默病药物非临床药效学评价体系的探索. 黄龙舰，赵春阳，冯新红，兰嘉琦，唐婧姝，王庆利*，彭英*. 药学学报. 2020
10. Genotoxicity Assessment of Drinking Water Disinfection By-products (DBPs) by DNA Damage and Repair Pathway Profiling Analysis. Jiaqi Lan, Sheikh Mokhlesur Rahman, Na Gou, Tao Jiang, Micheal J. Plewa, Akram Alshawabkeh and April Z.Gu*. Environmental science & technology. 2018
11. A quantitative toxicogenomics assay for high-throughput and mechanistic genotoxicity assessment and screening of environmental pollutants. Jiaqi Lan, Na Gou, Sheikh Mokhles Rahman, Ce Gao, Miao He, and April Z. Gu*. Environmental science & technology. 2016
12. Toxicity Assessment of 4-Methyl-1-cyclohexanemethanol and Its Metabolites in Response to a Recent Chemical Spill in West Virginia, USA. Jiaqi Lan, Man Hu, Ce Gao, Akram Alshawabkeh, April Gu*. Environmental Science & Technology. 2015
13. Comparative and Mechanistic Genotoxicity Assessment of Nanomaterials via A Quantitative Toxicogenomics Approach Across Multiple Species. Jiaqi Lan, Na Gou, Ce Gao, Miao He, April Gu*. Environmental science & technology. 2014
14. Evaluation of cytotoxic, genotoxic and inflammatory responses of nanoparticles from photocopiers in three human cell lines. Madhu Khatri*, Dhimiter Bello*, Anoop K Pal, Joel M Cohen, Susan Woskie, Thomas Gassert, Jiaqi Lan, April Z Gu, Philip Demokritou and Peter Gaines. Particle and Fibre Toxicology. 2013
15. Genome-wide functional and stress response profiling reveals toxic mechanism and genes required for tolerance to benzo[a]pyrene in S. cerevisiae. Sean Timothy Francis O'Connor, Jiaqi Lan, Matthew North, Alexandre Loguinov, Luoping Zhang, Martyn T Smith, April Gu, Chris Vulpe*. Frontiers in genetics. 2012
16. Transport behavior of ellagic acid of pomegranate leaf tannins and its correlation with total cholesterol alteration in HepG2 cells. Jiaqi Lan, Fan Lei, Lei Hua, Yugang Wang, Dongming Xing, Lijun Du*. Biomedical Chromatography. 2009
17. Determination of brazilein in rat plasma after intravenous administration by HPLC. Jiaqi Lan, Jun Hu, Bonan Li, Dongming Xing, Chengcheng Liu, Wei Wang, Lijun Du*. Biomedical Chromatography. 2008
18. Cerebral Ischemia Reperfusion Exacerbates and Pueraria Flavonoids Attenuate Depressive Responses to Stress in Mice. Jiaqi Lan, Bin Yan, Yu’nan Zhao, Daoyi Wang, Jun Hu, Dongming Xing, Lijun Du. Tsinghua Science and Technology*. 2008
19. 黄芩总黄酮对大鼠脑核团单胺类递质的影响. 兰嘉琦，张陆军，邢东明，吴昊，胡珺，杜力军*. 中国药理学通报. 2007