1. 微生物活性天然产物的发现：从特殊生境微生物、食药用真菌等中发现新颖结构活性天然产物，为新药研制提供先导化合物。
2. 活性天然产物的生物合成和生物催化：解析结构独特的活性天然产物的生物合成途径，从中挖掘关键酶，通过构建异源表达或生物催化体系，实现天然产物及其衍生物的绿色生物合成。

1. The flying spider-monkey tree fern genome provides insights into fern evolution and arborescence. Huang X†, Wang WL†, Gong T†, Wickell D†, Kuo LY, Zhang X, Wen JL, Kim H, Lu F, Zhao HS, Chen Song, Li H, Wu WQ, Yu CJ, Chen S, Fan W, Chen S, Bao XQ, Li L, Zhang D, Jiang LY, Yan XJ, Liao ZY, Zhou GK, Guo YL, Ralph J, Sederoff RR, Wei HR*, Zhu P*, Li FW*, Ming R*, Li QZ*. Nature Plants, 2022, 8(5): 500-512. (IF=18.0)
2. A fungal CYP from Beauveria bassiana with promiscuous steroid hydroxylation capabilities. Peng Y, Wang Y, Chen TJ, Chen JJ, Yang JL, Gong T*, Zhu P*. Chinese Chemical Letters, 2024, 35(5): 108818. (IF=8.9)
3. Unusual (2R,6R)-bicyclo[3.1.1]heptane ring construction in fungal ɑ-trans-bergamotene biosynthesis. Wen YH, Chen TJ, Jiang LY, Li Li, Guo MB, Peng Y, Chen JJ, Pei F, Yang JL, Wang RS, Gong T*, Zhu P*. iScience, 2022, 25(4): 104030. (IF=5.8)
4. Microbial biotransformation to obtain stilbene methylglucoside with GPR119 agonistic activity. Peng Y†, Huan Y†, Chen JJ, Chen TJ, Lei L, Yang JL, Shen ZF, Gong T*, Zhu P*. Frontiers in Microbiology, 2023, 14: 1148513. (IF=4.0)
5. Tetrocarcin Q, a New Spirotetronate with a Unique Glycosyl Group from a Marine-Derived Actinomycete Micromonospora carbonacea LS276. Gong T, Zhen X, Li XL, Chen JJ, Chen TJ, Yang JL, Zhu P*. Marine Drugs, 2018, 16, 74. (IF=3.8)