1. 新药研发过程中药代动力学性质的早期评价。
2. 新药临床前药代动力学研究。
3. 药物代谢酶和转运蛋白的调控。
4. PBPK/PD模型研究
5. 天然产物/中药多成分的药代动力学及相关研究

1. Hongfei Mu1, Qiong Jin1, Jia Tang, Lisha Ye, Baolian Wang *,Pharmacokinetics and related gender difference studies of four active components of Codonopsis Pilosula by LC-MS/MS determination, Journal of Ethnopharmacology, 337 (2025) 118899 .
2. Jia Tang, Lisha Ye, Baolian Wang *. Absorption, distribution, metabolism, and excretion (ADME) of R,S-Goitrin in Radix Isatidis in rats by LC-MS/MS determination. Fitoterapia 183 (2025) 106514.
3. Yanan Wang , Fengyu Han , Lisha Ye, Tongqiang ShangGuan, Shengci Fan, Yihuan She, Xiuling Yu*, Dongmei Wang*, Baolian Wang*. Saorilao Qingfei Zhike Capsule alleviated inflammation and bronchial remodeling in LPS and CS-induced COPD via MAPK signaling pathway. , Journal of Ethnopharmacology, 350 (2025) 119993.
4. Xuechen Li; Dongting Chen; Chufan Qi; Yajun Yang; Kaijing Guo; Chen Ma; Jinying Tian; Jiang Li; Lu Zhang; Baolian Wang*; Zhiyan Xiao*; Fei Ye* ; Identification of a novel xanthineoxidoreductase inhibitor for hyperuricemia treatment with high efficacy and safety profile, Biomedicine & Pharmacotherapy, 178 (2024) 117223.
5. Hanyu Sun, Tingting Du, Minjian Yang, Xue Liu, Xi Xue, Kai Chen, Xuli Lang, Xiaoguang Chen,* Baolian Wang,* Xiaojian Wang*. Targeting the Subpocket Enables the Discovery of Thiadiazole−Pyridazine Derivatives as Glutaminase C Inhibitors[J]. ACS Medicinal Chemistry Letters, 14(2023)1455-1466.
6. Chengjuan Chen1, Ningyu Fan1, Chengbo Xu, Shuai Shao, Gaona Shi, Yu Zhou, Yazi Wei, Lei Wu, Baolian Wang*, Jiangong Shi*, Tiantai Zhang*. A synthetic derivative of bioactive constituents from Isatis indigotica ameliorates hypersensitivity and arthritis by inhibiting JAK2-STAT3 pathway in mice[J]. International Immunopharmacology, 124(2023)110884.
7. Jianzhao Niu; Hanhan Huang; Ming Ji; Wenjing Zhan; Yin Huang; Lingyun Ma*; Baolian Wang*; Qian Liu*; Bioequivalence Analysis of Terazosin Hydrochloride Tablets Based on Parallel Artiffcial Membrane Permeability Analysis, Pharmaceuticals, 17(2024)1024.
8. Hongfei Mu; Lisha Ye; Baolian Wang*; Detailed resume of S-methyltransferases: Categories, structures, biological functions and research advancements in related pathophysiology and pharmacotherapy, Biochemical Pharmacology , 226 (2024) 116361.
9. Xinbo Wang; Xuli Lang; Fenghe Wang; Huixin Tan; Gang Li; Peng Li; Jinping Hu; Baolian Wang*; Yan Li. Simultaneous determination of NTB-3119, a novel anti-tuberculosis agent, and its major metabolites in mouse plasma by LC-MS/MS and its application in preclinical pharmacokinetics study[J]. Journal of Pharmaceutical and Biomedical Analysis, ,224(2023): 115172
10. Jianwei Jiang, Yuke Liu, Xiao Liu, Dongfeng Zhang, Haihong Huang, Baolian Wang*, Li Sheng*, Yan Li. Simultaneous determination of a novel oxazolidinone anti-tuberculosis OTB-658 and its metabolites in monkey blood by LC-MS/MS[J]. Journal of Chromatography B, 1167(2021):122552.