ZHANG Xiaoying
2018 – present: Associate professor, Institute of Materia Medica, CAMS & PUMC
2016 – 2018: Assistant professor, Institute of Materia Medica, CAMS & PUMC
2015 – 2016: Staff scientist, College of Medicine, University of Tennessee Health Science Center, USA
2014 – 2015: Postdoctoral fellow, College of Medicine, University of Tennessee Health Science Center, USA
2009 – 2014: Postdoctoral fellow, City of Hope National Medical Center & Beckman Research Institute, USA
2004 – 2009: PhD, School of Life Sciences, Capital Normal University
1. F1099L-CFTR has impaired channel function and associates with mild disease phenotypes in two pediatric patients. Life (Basel), 2021,11(2):131.
2. A novel S1P1 modulator IMMH002 ameliorates psoriasis in multiple animal models. Acta Pharm Sin B, 2020,10(2): 276-288.
3. Validating a Selective S1P1 Receptor Modulator Syl930 for Psoriasis Treatment. Biol Pharm Bull, 2018,41(4): 592-596.
4. A Series of Enthalpically Optimized Docetaxel Analogues Exhibiting Enhanced Antitumor Activity and Water Solubility. J Nat Prod, 2018,81(3): 524-533.
5. Analysis of liver tumor-prone mouse models of the Hippo kinase scaffold proteins Rassf1a and Sav1. Cancer Res, 2016, 76(9):2824-35.
6. Lumacaftor/ivacaftor combination for cystic fibrosis patients homozygous for Phe508del-CFTR. Drugs Today (Barc), 2016, 52(4):229-237.
7. 3623 G>A mutation encodes a CFTR protein with impaired channel function. Respir Res, 2016, 17(1):8.
8. Longitudinal epigenetic and gene expression profiles analyzed by three –component analysis reveal down-regulation of genes involved in protein translation in human aging. Nucleic Acids Res, 2015, 43(15):e100.
9. The tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinase MST1 and MST2. J BiolChem, 2011, 286(8): 6253-61.
10. CDK5RAP2 is required for spindle checkpoint function. Cell Cycle, 2009, 8(8): 1206-16.
