ZHANG Sen
Zhang Sen obtained a bachelor's degree in biochemistry from Shandong University in 2002, and then received a master's degree and a doctor's degree from Peking Union Medical College, China, respectively. From 2008 to 2011, he as a visiting scholar at Nanyang Technological University, Singapore. He has been engaged in the research and development of novel drugs for almost 20 years. He has conducted and participated in a number of national grants including basic research and R & D of the new drugs. As the first author or corresponding author, he has published more than 20 SCI indexed papers, applied for 10 patents and 3 new drugs are currently under research.
1. Esculetin alleviates murine lupus nephritis by inhibiting complement activation and enhancing Nrf2 signaling pathway. Food Science and Human Wellness, 2021, in press.
2. New insight into long non-coding RNAs associated with bone metastasis of breast cancer based on an integrated analysis. Cancer Cell international, 2021, DOI: 10.1186/s12935-021-02068-7.
3. Druggability of lipid metabolism modulation against renal fibrosis. Acta Pharmacologica Sinica, 2021, DOI: 10.1038/s41401-021-00660-1.
4. Long non-coding RNAs: from disease code to drug role. Acta Pharmaceutica Sinica B, 2021, 11(2), 340-354.
5. Prediction value of serum NGAL in the diagnosis and prognosis of experimental acute and chronic kidney injuries. Biomolecules, 2020, 10(7):981. doi: 10.3390/biom10070981.
6. Seeking for correlative genes and signaling pathways with bone metastasis from breast cancer by integrated analysis. Frontiers in Oncology. 2019, 9:138. DOI: 10.3389/fonc.2019.00138.
7. Coumarin glycosides from Hydrangea paniculata slow down the progression of diabetic nephropathy by targeting Nrf2 anti-oxidation and smad2/3-mediated profibrosis. Phytomedicine, 2019,57, 385-395.
8. Nicousamide attenuates renal dysfunction and glomerular injury in remnant kidneys by inhibiting TGF-β1 internalisation and renin activity. European journal of pharmacology, 2019, 845:74-84.
9. Icotinib enhances lung cancer cell radiosensitivity in vitro and in vivo by inhibiting MAPK/ERK and AKT activation. Clinical and experimental pharmacology and physiology. 2018;45(9):969-977.
10. Total Coumarins from Hydrangea paniculata Show Renal Protective Effects in Lipopolysaccharide-Induced Acute Kidney Injury via Anti-inflammatory and Antioxidant Activities. Frontiers in Pharmacology. 2017;8(872). DOI: 10.3389/fphar.2017.00872.
