YANG Xiuying
Yang Xiuying is working at the National Drug Screening Center of the Institute of Materia Medica, Chinese Academy of Medical Sciences. She got her PhD degree in pharmacology from Peking Union Medical College in July 2007. In 2008 and 2014, She conducted post-doctoral research on diabetes at McGill University Health Science Center in Canada and the University of Oklahoma in the United States. Her main research interests are to study the disease mechanisms of metabolic diseases and discover new drugs for the treatment of diabetes, obesity, and the complications. Her research mainly focuses on the establishment of drug screening models for metabolic diseases, especially GPCR-related drug screening and pharmacological study.
1. Puerarin ameliorates skeletal muscle wasting and fiber type transformation in STZ induced type 1 diabetic rats. Biomedicine and pharmacotherapy. 2021;133:110977.
2. Effects of fasting on the expression pattern of FGFs in different skeletal muscle fibre types and sexes in mice. Biol Sex Differ. 2020;11(1):9.
3. Neuroprotective Effect of Salvianolic Acid A against Diabetic Peripheral Neuropathy through Modulation of Nrf2. Oxid Med Cell Longev. 2020: 6431459.
4. Lipid Profiling Reveals Browning Heterogeneity of White Adipose Tissue by Β3-Adrenergic Stimulation. Biomolecules. 2019;9(9):444.
5. Muscle-generated BDNF is a sexually dimorphic myokine that controls metabolic flexibility. Sci Signal 2019; 12(594).
6. Chronic Urotensin-II administration improves whole-body glucose tolerance in high-fat diet-fed mice Front. Endocrinol., 2019;10:453.
7. Glucose consumption assay discovers coptisine with beneficial effect on diabetic mice. Eur J Pharmacol. 2019;859:172523.
8. Effect of skeletal muscle phenotype and gender on fasting-induced myokine expression in mice. Biochem Biophys Res Commun. 2019;514(2):407-414.
9. Interaction of CREB and PGC-1alpha Induces Fibronectin Type III Domain-Containing Protein 5 Expression in C2C12 Myotubes. Cell Physiol Biochem. 2018. 50(4): 1574-1584.
10. Low molecular weight heparin does not reduce miscarriages in non-thrombophilic IVF/ICSI-treated women. Acta Obstet Gynecol Scand. 2018 14.
11. BDNF mimetic alleviates body weight gain in obese mice by enhancing mitochondrial biogenesis in skeletal muscle. Metabolism. 2018; 87: 113-122.
12. Efficacy of low-molecular-weight heparin on the outcomes of IVF/ICSI pregnancy in non-thrombophilic women: a meta-analysis. Acta Obstet Gynecol Scand. 2018; 97(9): 1061-1072.
13. Puerarin Mitigates Diabetic Hepatic Steatosis and Fibrosis by Inhibiting TGF-β Signaling Pathway Activation in Type 2 Diabetic Rats. Oxid Med Cell Longev. 2018; 2018: 4545321.
14. Salvianolic Acid A Protects Against Diabetic Nephropathy through Ameliorating Glomerular Endothelial Dysfunction via Inhibiting AGE-RAGE Signaling. Cell Physiol Biochem, 2017;44:2378-2394
15. Tannerella forsythia and coating color on the tongue dorsum, and fatty food liking associate with fat accumulation and insulin resistance in adult catch-up fat. Int J Obes (Lond). 2017.
16. Tumor Necrosis Factor-alpha Promotes Phosphoinositide 3-Kinase Enhancer A and AMP-Activated Protein Kinase Interaction to Suppress Lipid Oxidation in Skeletal Muscle. Diabetes, 2017,66(7):1858-1870.
17. The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation. Nat Commun, 2016;7:11378.
1. Experimental Pharmacology (2nd Ed). Chief editor: Du Guan-hua/Co-edited by Yang Xiu-ying et al. Higher Education Press. 2021. ISBN: 978-7-04-054780-1.
2. Overview of ancient and modern research on "toxicity" of traditional Chinese Medicinal Materials. Chief editor: Du Guan-hua/Co-edited by Yang Xiu-ying et al. China Medical Science and Technology Press, 2019. ISBN: 978-7-5214-0668-9.
3. Natural Small Molecule Drugs from Plants (English version). Chief editor: Du Guan-hua/Co-edited by Yang Xiu-ying et al. Springer Press, 2019. ISBN: 978-981-10-8022-7.
4. Natural Small Molecule Drugs from Plants (Chinese version). Chief editor: Du Guan-hua/Co-edited by Yang Xiu-ying et al. People's Medical Publishing House, 2018. ISBN: 9787117248709.
5. The chemistry, pharmacology and clinical therapeutic effects of Danshen. Chief editor: Zhang Jun-tian, Du Guan-hua/Co-edited by Yang Xiu-ying, at al. Chemical Industry Press, 2013. ISBN: 9787122174819.
1. 2017: Chinese medical science and technology award. Third prize, Chinese Medical Association. China.
2. 2012: University scientific research outstanding achievement award (Science and Technology). Second prize of Natural Science Award, Peking Union Medical College. China
3. 2011: Chinese medical science and technology award. Third prize, Chinese Medical Association. China.
