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YANG Shiying
Associate Professor

Department :

Research Center of Polymorphic Drugs

Platform :

Beijing Key Laboratory of Polymorphic Drugs

Contact Details

Lu Yang's group
ysy@imm.ac.cn
Brief Introduction

Education background

2001 – 2005: Shenyang Pharmaceutical University, Bachelor of Pharmacy Engineering

2005 – 2010: Chinese Academy of Medical Sciences & Peking Union Medical College, Doctor of Pharmaceutical Analysis

Work experience

2010 – Present: Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College

Research area

Studies of polymorphism and co-crystals of APIs, including: polymorphic screening, characterization analysis, druggability evaluation and polymorphic quality control of innovative drugs and lead compounds. Yang Shiying has presided over and undertaken and participated in national and provincial major scientific and technological projects. More than 20 scientific papers and 5 monographs have been published. More than 50 invention patents have been applied for, with 11 authorized.

Achievements

Papers

1. Screening, Characterization and Evaluation of Mangiferin Polymorphs. Natural Products and Bioprospecting. 2020.

2. Certification of a New Certified Reference Material of Honokiol. Analytical and Bioanalytical Chemistry, 2015, 407:5849–5855.

3. Characterization of a new anhydrous form of Rotundine and itsmonohydrate. Journal of Molecular Structure, 2015,1095:79-86.

4. Development of a new certified reference material of high-purity chrysin for the quality control of traditional Chinese medicine. Accreditation and Quality Assurance, 2016,21(4): 287-293.

5. Qualitative Detection for Polymorphs in Solid Pharmaceutical Preparations by Powder X-ray Diffraction. Herald of Medicine. 2015, 34(7): 930-934.

6. Quantitative analysis of nitrendipine polymorph using differential scanning calorimetry. Chinese Journal of New Drugs. 2015, 24(12): 1423-1426.

7. Research on certified reference material of emodin in rhubarb and itsalcohol extract,water extract. Chinese Journal of Chinese Materia Medica, 2016, 41(3): 456-462.

8. Present Situation and Progress of the Research for Polymorphic Chemical Drugs in China. Herald of Medicine. 2019,38(2):177-182

9. Certification of reference materials foranalysis of isoflavones genistin and genistein in soyproducts. Analytical Methods,2016.  

10. Chemical constituents from the leaves and stems of Schisandra rubriflora. J Nat Prod,2010.

Books

1. Polymorphic Drugs 2019 (2nd Edition). Lu, Y., Du, G.H, Yang, S.Y. etc. Edited by Cheng Y.  People's Medical Publishing House , Pages 52-87,294-372. Print ISBN: 978-7-117-28034-1.

2. Polymorphic Drugs 2009 (1st Edition). Lu, Y., and Du, G.H, Yang, S.Y. etc. Edited by Gao B. and Kuang L.J.  People's Medical Publishing House , Pages 69-107. Print ISBN: 978-7-117-11571-1.

3. Natural Small Molecule Drugs from Plants. Du, G.H., Fang L.H., Lu, Y., Chen N.H., Wang J.H., Qin X.M, Yang, S.Y. etc.. Edited by Cao J.H.  People's Medical Publishing House, Pages 158-161. Print ISBN: 978-7-117-24870-9.

4. Natural Small Molecule Drugs from Plants. Du, G.H., Fang L.H., Lu, Y., Chen N.H., Wang J.H., Qin X.M, Yang, S.Y. etc. People's Medical Publishing House, Pages 439-444. Print ISBN: 978-7-117-29101-9.

Honors & Awards

1. 2016, State Scientific & Technological Progress Award, Second Prize, China.

2. 2014, Beijing Scientific & Technological Progress Award, First Prize, Beijing, China.