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YANG Qingyun Principal Investigator
Associate Professor

Department :

Department of New Drug Research and Development

Platform :

Contact Details

Yang Qingyun's group
yqy@imm.ac.cn
Brief Introduction

Yang Qingyun obtained her master's and doctorate degrees from Peking Union Medical College, and joined the Institute of Materia Medica in 2006. She has presided over five basic scientific research and technology development projects and central public welfare scientific research institutes. She is either in charge of or participates in 10 projects, including provincial/municipal science and technology plan projects, medical and health science projects, and so on. She has completed three innovative drug R&D projects, one of which is currently in Phase II clinical trials. She has developed over 10 generic drugs, all of which have passed clinical reviews.

She has published over 30 research papers, 15 of which were included in SCI. She has applied for over 20 domestic patents, 10 of which have already been authorized; and 2 international patents, 1 of which has been patented in Europe. Yang's research areas focus on quality control and quality standard research on innovative drugs and generic drugs; new technologies and methods for pharmaceutical analysis.

Achievements

Papers

1. Quantitative 1H nuclear magnetic resonance method for assessing the purity of dipotassium Glycyrrhizinate.  Molecules , 2021, 26(12): 3549.

2. Development and Validation of LC-MS/MS for Analyzing Potential Genotoxic Impurities in Pantoprazole Starting Materials.  Journal of Analytical Methods in Chemistry , 2020 (3): 1-8.

3. Versatile and Enantioselective Total Synthesis of Naturally Active Gnetulin.  Adv. Synth. Catal. 2019, 361, 3768-3776. DOI: 10.1002/adsc.201900336.

4. Quantitative proton nuclear magnetic resonance for the quantitative analysis of tadalafil and its tablets.  Molecules  2015, 20, 12114-12124.

5. Wensheng Zheng. Cyanogenetic glucoside derivatives from flaxseed meal.  Fitoterapia , 2015, 106,78-83.

6. Identification and Synthesis of Impurities in Pinocembrin—A New Drug for the Treatment of Ischemic Stroke.  Chinese Journal of Chemistry , 2012,30,1315-1319.

7. A new triglucosylated naphthalene glycoside from Aloe vera L. Fitoterapia, 2010, 81 (1), 59-62.

8. BACE-1 Inhibitory Chromone Glycosides from Aloe sp. Plants.  Planta Medica 2008, 74 (5), 540-545.

9.    Synthesis and enantiomeric resolution of (6)-pinocembrin.  J Asian Nat. Prod. Res . 2008, 10(10), 999-1002.

10. Bioactive Coumarins from Boenning- hausenia sessilicarpa.  J Asian Nat. Prod. Res. 2007, 9 (1): 59-65.

Books

Honors & Awards

1. The Third Prize of 2014 Chinese Pharmaceutical Association Science and Technology Award, China.

2. The First Prize of 2014 Beijing Science and Technology Award, China.

3. The Third Prize of 2020 Jiangxi Science and Technology Invention Award, China.