YANG Jinling
Professor Yang Jinling got her bachelor's degree and master's degree from Shandong University in 1991 and 1994, and doctor's degree from the Institute of Botany, Chinese Academy of Sciences in 1997. Since then, she has been working at the Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College. She majors in biosynthesis of natural medicines, which focuses on solving the problem of drug source shortage and finding drug leads based on synthetic biology. Her research interests include discovery of biosynthetic genes, elucidation of enzyme mechanism, analysis of biosynthetic pathway, and construction of microbial cell factories of natural products. She has published more than 60 papers and applied for 10 patents.
1. Construction and optimization of microbial cell factories for sustainable production of bioactive dammarenediol-II glucosides. Green Chemistry , 2019, 21: 3286-3299.
2. Production of a bioactive unnatural ginsenoside by metabolically engineered yeasts based on a new UDP-glycosyltransferase from Bacillus subtilis. Metabolic Engineering , 2017, 44: 60-69.
3. Enzymatic synthesis of unnatural ginsenosides using a promiscuous UDP-glucosyltransferase from Bacillus subtilis. Molecules , 2018, 23: 2797.
4. Progress on the studies of the key enzymes of ginsenoside biosynthesis. Molecules , 2018, 23: 589.
5. High-level soluble expression of human Cu,Zn superoxide dismutase with high activity in Escherichia coli. World Journal of Microbiology and Biotechnology , 2020, 36: 106.
6. Expression, purification and characterization of an analgesic peptide from Buthus martensii Karsch in Pichia pastoris. World Journal of Microbiology and Biotechnology , 2009, 25: 2053-2056.
7. Enhancement of recombinant BmK AngM1 production in Pichia pastoris by regulating gene dosage, co-expressing with chaperones and fermenting in fed-batch mode. Journal of Asian Natural Products Research , 2017, 19(6): 581-594.
8. Non-support of species complex hypothesis of Cordyceps sinensis by targeted rDNA-ITS sequence analysis. Mycosystema , 2009, 28(5): 724-730.
9. Cloning and expression of human lectin-like oxidized low density lipoprotein receptor-1 in Pichia pastoris. Biotechnology Letters , 2005, 27(1): 49-52.
10. Phylogenetic diversity of culturable fungi associated with two marine sponges: Haliclona simulans and Gelliodes carnosa, collected from the Hainan Island coastal waters of the South China Sea. Fungal Diversity , 2010, 42: 1-15.
