XIE Ping
Principal Investigator
Xie Ping is working as a professor and DS supervisor with the Institute of Materia Medica, Chinese Academy of Medical Sciences. His research focus was on total synthesis of natural products, structure modification and new drug R&D. For drug research and development, he worked as the head of the synthesis and was deeply involved in the preclinical study of Xiaokeliu'an (Phase II) and Fenle'an (Phase I). He has published more than 10 SCI research papers and filed 9 patents in recent years.
1. Total Synthesis of the Proposed Structure of Characellide B. Org. Lett., 2021, 23, 3680-3684.
2. Discovery of CAPE derivatives as dual EGFR and CSK inhibitors with anticancer activity in a murine model of hepatocellular carcinoma. Bioorganic Chemistry, 2021, 107, 104536.
3. Total Synthesis of Bysspectin A. Tetrahedron, 2019, 75, 3101-3107.
4. Asymmetric total synthesis of (t)-isocryptotanshinone and formal synthesis of (-)-cryptotansh- inone. Tetrahedron, 2019, 75, 3962-3967.
5. Enantioselective Total Synthesis of Colomitides and their Absolute Configuration Determina- tion and Structural Revision. Org. & Bio. Chem., 2017, 15, 3728- 3735.
6. Discovery of novel N-substituted-prolinamido indazoles as potent Rho kinase inhibitors and vasorelaxation agents. Molecules, 2017, 22, 1766-1781.
7. Total Synthesis and Stereochemical Revision of Xiamenmycin A. Organic & Biomolecular Chemistry, 2016, 14,1805-1813.
8. An approach to (±)-Lingzhiol. Org. Lett., 2016, 18, 1944-1946.
9. A practical synthesis of chiral tricyclic cyclopenta[b]benzofuran, a key intermediate of Beraprost. Organic & Biomolecular Chemistry, 2016, 14, 7715 –7721.
10. Total Synthesis of Xiamenmycin C and All of Its Stereoisomers: Stereochemical Revision. Journal of Asian Natural Products Research, 2016, 18(10), 976-987.
