WANG Zhaohui
Principal Investigator
Wang Zhaohui holds a B.S. from Zhengzhou University, an M.S. from Shenyang Pharmaceutical University, and a Ph.D. from Peking University. Each of these degrees is in the field of pharmaceutics. After completing his education, Wang obtained the opportunity of postdoctoral training at Purdue University and University of Texas Southwestern Medical Center at Dallas. In Oct. 2020, he joined the faculty of the Institute of Materia Medica, Chinese Academy of Medical Science as principal investigator.
Wang's research focus is the development of smart drug delivery systems for cancer immunotherapy. He is also interested in the clinical translation of nanotherapeutics, with two related works transferred to OncoNano Medicine, Inc. He has published about 30 peer-reviewed papers in prestigious journals, including Nature Nanotechnology, Angewandte Chemie International Edition, Biomaterials, Journal of Immunology, and these papers are frequently cited in the pharmaceutical field.
1. A STING-activating nanovaccine for cancer immunotherapy. Nature Nanotechnology . 2017, 12, 648-654.
2. A redox-activatable fluorescent sensor for the high-throughput quantification of cytosolic delivery of macromolecules. Angewandte Chemie International Edition . 2017, 129, 1339-1343.
3. Innate immune activation by cGAMP-PC7A nanoparticles leads to potent and long-acting antiretroviral response against HIV-1. Journal of Immunology . 2017, 199, 3840-3848.
4. A specific peptide ligand-modified lipid nanoparticle carrier for the inhibition of tumor metastasis growth. Biomaterials. 2013, 34, 756-764.
5. LyP-1 modification to enhance delivery of artemisinin or fluorescent probe loaded polymeric micelles to highly metastatic tumor and its lymphatics. Molecular Pharmaceutics. 2012, 9, 2646-2657.
6. The use of a tumor metastasis targeting peptide to deliver doxorubicin-containing liposomes to highly metastatic cancer. Biomaterials . 2012, 33, 8451-8460.
7. Trimethylated chitosan-conjugated PLGA nanoparticles for the delivery of drugs to the brain. Biomaterials. 2010, 31, 908-915.
Stimuli-responsive and triggered drug delivery systems. Wang Z, Zhang X, Huang G, and Gao J. Edited by Amiji M and Singh A. The Royal Society of Chemistry , Pages 51-82. Print ISBN: 978-1-78801-113-6.
