Dr. Wang Yuhong studies cardiovascular and molecular pharmacology. From 1997 to 2008, she got bachelor's degree in clinical medicine, master's degree in pharmacology and doctor's degree in physiology from Hebei Medical University. From 2008 to 2014, she worked as a postdoctoral fellow in Virginia Commonwealth University. In December 2014, she joined the Department of pharmacology, Institute of pharmacy, Chinese Academy of Medical Sciences, and was employed as an associate researcher in 2017. She has published 21 SCI papers.
1. Auxiliary subunits control biophysical properties and response tocompound NS5806 of the Kv4 potassium channel complex. FASEB Journal. 2020.
2. The cajanine derivative LJ101019C regulates the proliferation and enhances the activity of NK cells via Kv1.3 channel-driven activation of the AKT/mTOR pathway. Phytomedicine. 2020
3. Upregulation of phosphoinositide 3‑kinase prevents sunitinib‑induced cardiotoxicity in vitro and in vivo. Archives of Toxicology. 2019.
4. The cardiac electrophysiology effects of higenamine in guinea pig heart. Biomed Pharmacother. 2019.
5. Utility of the JT peak interval and the JT area in determining the proarrhythmic potential of QT-shortening agents. J Cardiovasc Pharmacol Ther. 2018.
6. Distinct protein kinase C isoenzyme mediates inhibitory effects of different G-protein coupled receptors on cardiac rapidly activating delayed rectifier K+ current. Br J Pharmacol. 2017.
7. Adult ventricular myocytes segregate KCNQ1 and KCNE1 to keep the IKs amplitude in check until when larger IKs is needed. Circ Arrhythm Electrophysiol. 2017.
8. JPH-2 interacts with Cai-handling proteins and ion channels in dyads: Contribution to premature ventricular contraction-induced cardiomyopathy. Heart Rhythm. 2016.
9. A ligand-based virtual screening approach to identify small molecules as hERG channel activators. Combinatorial Chemistry & High Throughput Screening. 2015.
10. Probing binding sites and mechanisms of actions of and Iks activation by computations and experiments. Biophys J. 2015.
11. Cellular mechanism of premature ventricular contraction-induced cardiomyopathy. Heart rhythm. 2014.
12. Down-regulation of Ether-a-go-go-Related gene potassium channel protein through sustained stimulation of AT1 receptor by angiotensin II. Biochem Biophys Res Commun. 2014.