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WANG Wei Principal Investigator
Professor

Department :

Department of Biosynthesis of Natural Products

Platform :

State Key Laboratory of Bioactive and Function of Natural Medicines
NHC Key Laboratory of Biosynthesis of Natural Products

Contact Details

Wang Wei's group
wwang@imm.ac.cn
Brief Introduction

Dr. Wang Wei received his bachelor's degree (1993) from QuFu Normal University, master's degree (1999) from Capital Normal University and doctoral degree (2002) from Peking Union Medical College. He has been working at the Institute of Materia Medica (IMM) of Chinese Academy of Medical Sciences (CAMS) since 2002. He worked as postdoctoral fellow at the Nan Technology University from 2006 to 2008. Now he is engaged in modern biological technology development and drug design research. He has published more than 40 research papers and applied for 6 patents, four of which have been authorized.

Achievements

Papers

1. cDNA Isolation and Functional Characterization of UDP-glucose 4-epimerase Family from Davallia divaricate. Journal of Asian Natural Products Research, 2020, 22, 271-278.

2. Low-Level Organic Solvents Improve Multienzyme Whole-Cell Catalytic Synthesis of Myricetin-7-O-Glucuronide. Catalysts, 2019, 9,970

3. Identification and Characterization of Two New 1‑O‑Acyl-glucose-ester Forming Glucosyltransferases from Erigeron breviscapus. Journal of Agricultural and Food Chemistry, 2019, 67, 2848-2855.

4. Acrolein-stressed threshold adaptation alters the molecular and metabolic bases of an engineered Saccharomyces cerevisiae to improve glutathione production. Scientific Reports, 2018, 8, 4506.

5. Engineering Saccharomyces cerevisiae with the deletion of endogenous glucosidases for the production of flavonoid glucosides. Microbial Cell Factories, 2016, 15, 134.

6. Systems metabolic engineering of Escherichia coli to enhance the production of flavonoid Glucuronides. RSC Advances, 2016, 6, 33622–33630.

7. Three-pathway combination for glutathione biosynthesis in Saccharomyces cerevisiae. Microbial Cell Factories, 2015, 14, 139.

8. Autoprocessing: an essential step for expression and purification of enterovirus 71 3Cpro in  Escherichia coli . Biotechnology Letters. 2013, 35(11), 1845-1852.

9. Discovery of A Linear Cyclotide from the Bracelet Subfamily and Its Disulfide Mapping by Top-Down Mass Spectrometry. Journal of Biological Chemistry, 2011, 286(52): 44833-44844.

Books

Honors & Awards