SONG Junke
Education background
09/2010 – 06/2015: Peking Union Medical College, Pharmacology
09/2006 - 06/2010: Shenyang Pharmaceutical University, Basic Pharmacy
Work experience
09/2020 - present: Institute of Materia Medica, CAMS, Associate professor, Neuropharmacology and pharmacokinetics
09/2015 - 09/2020: Institute of Materia Medica, CAMS, assistant professor, neuropharmacology and pharmacokinetics
1. The comprehensive study on the therapeutic effects of baicalein for the treatment of COVID-19 in vivo and in vitro. Biochemical Pharmacology, 2021, 183: 114302.
2. Inhibition of FOXO3a/BIM signaling pathway contributes to the protective effect of salvianolic acid A against cerebral ischemia/reperfusion injury. Acta Pharmaceutica Sinica B, 2019, 9(3): 505-515.
3. Activation of Nrf2 signaling by salvianolic acid C attenuates NF-κB mediated inflammatory response both in vivo and in vitro. International Immunopharmacology, 2018, 63: 299-310.
4. Determination of salvianolic acid C in rat plasma using liquid chromatography-mass spectrometry and its application to pharmacokinetic study. Biomedical Chromatography, 2016, 30(3): 376-383.
5. Pharmacokinetic study of salvianolic acid D after oral and intravenous administration in rats. Acta Pharmaceutica Sinica B, 2015, 5(3): 246-253.
6. Preclinical studies of the potent and selective nicotinic α4β2 receptor ligand VMY-2-95. Molecular Pharmaceutics, 2015, 12(2): 393-402.
7. The strategies and techniques of drug discovery from natural products. Pharmacology and Therapeutics, 2020, 216: 107686.
8. Diterpene ginkgolides protect against cerebral ischemia/reperfusion damage in rats by activating Nrf2 and CREB through PI3K/Akt signaling. Acta Pharmacologica Sinica, 2018, 39(8): 1259-1272.
9. Salvianolic acid D alleviates cerebral ischemia-reperfusion injury by suppressing the cytoplasmic translocation and release of HMGB1-triggered NF-κB activation to inhibit inflammatory response. Mediators of Inflammation, 2020, 9049614.
10. Some pharmacokinetic parameters of salvianolic acid A following single-dose oral administration to rats. Pharmaceutical Biology, 2018, 56(1): 399-406.
11. Salvianolic acid A attenuates ischemia reperfusion induced rat brain damage by protecting the blood brain barrier through MMP-9 inhibition and anti-inflammation. Chinese Journal of Natural Medicines, 2018, 16(3): 184-193.
12. Pharmacokinetic study of salvianolic acid A in beagle dog after oral administration by a liquid chromatography-mass spectrometry method: a study on bioavailability and dose proportionality. Journal of Ethnopharmacology, 2013, 148(2): 617-623.
13. Pharmacokinetic study of baicalein after oral administration in monkeys. Fitoterapia, 2012, 83(3): 532-540.
1. Pharmacological Advances in Natural Product Drug Discovery. Academic Press, 2020, Pages 1-41, ISBN: 978-0-12-820185-5.
2. Natural Small Molecule Drugs from Plants. Springer, 2019, ISBN: 978-7-117-29101-9.
1. 2019, Chinese Medical Science and Technology Award, Second Prize, China.
2. 2014, Beijing Science and Technology Award, First Prize, China.
