SHI Jiangong
Principal Investigator
Dr. Shi Jiangong received his B.S. and Ph.D. degrees in 1985 and 1993 from Lanzhou Medical College and Lanzhou University, respectively. He worked in natural product chemistry as a postdoctoral fellow with Prof. Wang Han-Qing at Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (2 years); with Prof. Kenneth L. Rinehart at the University of Illinois at Urbana-Champaign (1.5 years); and with Prof. Abimael D. Rodriguez at the University of Puerto Rico (1 year). Then he joined the Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, and is currently a professor of medicinal chemistry and director of the Department of Natural Medicines Chemistry. His interests focus on minor and/or water-soluble constituents of commonly used traditional Chinese medicines. He has authored 200+ scientific publications and has 20+ licensed patents.
1. (+)-/(−)-Angelignanine, a pair of neolignan enantiomers with an unprecedented carbon skeleton from an aqueous extract of the Angelica sinensis root head. Chin Chem Lett. 2021, 32: 1657-1659.
2. Aconapelsulfonines A and B, seco C20-diterpenoid alkaloids deriving via Criegee rearrangements of napelline skeleton from Aconitum carmichaelii. Chin Chem Lett. 2021, 32: 33-36.
3. Minor alkaloids from an aqueous extract of the hook-bearing stem of Uncaria rhynchophylla. J Asian Nat Prod Res. 2021, 23: 513-526.
4. Structure, property, biogenesis, and activity of diterpenoid alkaloids containing a sulfonic acid group from Aconitum carmichaelii. Acta Pharm Sin B . 2020,10(10):1954-1965.
5. Indole alkaloid glycosides with a 1ʹ-(phenyl)ethyl unit from Isatis indigotica leaves. Acta Pharm Sin B . 2020, 10(5): 895-902.
6. Discovery, synthesis, and optimization of an N -alkoxy indolylacetamide against HIV-1 carrying NNRTI-resistant mutations from the Isatis indigotica root. Eur J Med Chem. 2020, 189: 112071.
7. Aconicatisulfonines A and B, analgesic zwitterionic C20-diterpenoid alkaloids with a rearranged atisane skeleton from Aconitum carmichaelii. Org Lett . 2019. 21(17): 6850-6854.
8. Aconicarmisulfonine A, a sulfonated C20-diterpenoid alkaloid from the lateral roots of Aconitum carmichaelii. Org Lett. 2018: 20:816-819.
9. C19-Diterpenoid alkaloid arabinosides from an aqueous extract of the lateral root of Aconitum carmichaelii and their analgesic activities. Acta Pharm Sin B . 2018, 8(3): 409-419.
10. Sulfur-enriched alkaloids from the root of Isatis indigotica. Acta Pharm Sin B . 2018, 8(6): 933-943.
Lignan Chemistry (Natural Product Chemistry Series). Chief Edited By Shi Jiangong. Chemical Industry Press. Print ISBN: 9787122065599.
1. 2014, Second Class Prizes of The State Scientific and Technological Progress Award.
2. 2014, Second Class Prizes of Beijing Science and Technology Award.
