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MA Chen Principal Investigator
Professor

Department :

Department of Pharmaceutical Analysis

Platform :

National Research Center for Analysis of Drugs and Metabolites
CAMS Key Laboratory of Anti-DR TB Innovative Drug Research

Contact Details

Ma Chen's group
mach@imm.ac.cn
Brief Introduction

Professor Ma Chen is the member of the 10th the Chinese Pharmacopoeia Commission (ChP) and vice chairman of Expert Committee of Chemical Products I of the 11th Chinese Pharmacopoeia Commission. She is a member of Chinese Drug Standards Editorial Board.

Her research fields involve in quality control and standard formulation of new drug substances and products, development of advanced analysis methods of drugs and metabolites, and analysis and evaluation of traditional Chinese medicines. She has also undertaken a number of national and provincial research projects.

Achievements

Papers

1. Identification of the New  In Vivo Metabolites of Ilaprazole in Rat Plasma after Oral Administration by LC-MS:  In Silico Prediction of the H+/K+-ATPase Inhibitor.  Molecules ,2021, 26(2), 459.

2. A Reliable HPLC-DAD Method for Simultaneous Determination of Related Substances in TBI-166 Active Pharmaceutical Ingredient.  Acta Chromatographica , 2020, 32(2): 80–85.

3. Pharmacokinetic Comparisons of Naringenin and Naringenin-Nicotinamide Cocrystal in Rats by LC-MS/MS.  Journal of Analytical Methods in Chemistry , 2020, 8364218.

4. Simultaneous Determination of 15 Sulfonate Ester Impurities in Phentolamine Mesylate, Amlodipine Besylate, and Tosufloxacin Tosylate by LC-APCI-MS/MS.  Journal of Analytical Methods in Chemistry , 2019, 4059765.

5. Plasma pharmacokinetics of isorhapontigenin, a novel derivative of stilbenes, in mice by LC-MS/MS method. Journal of Asian Natural Products Research, 2019, 21(9): 895-904.

6. Dual-Stimuli-Responsive Gut Microbiota-Targeting Berberine-CS/PT-NPs Improved Metabolic Status in Obese Hamsters.  Adv. Funct. Mater. , 2019, 1808197.

7. Characterization of degradation products and process-related impurity of sutezolid by liquid chromatography / electrospray ionization tandem mass spectrometry.  Journal of Pharmaceutical and Biomedical Analysis , 2019, 169:196-207.

8. Studies on the degradation impurity of linezolid tablets by UFLC-MS/MS.  Acta Pharmaceutica Sinica , 2017, 52 (6): 971-97.

9. Identification of forced degradation products of tedizolid phosphate by liquid chromatography/electrospray ionization tandem mass spectrometry.  Journal of Pharmaceutical and Biomedical Analysis, 2017, 139: 221–231.

10. Pharmacokinetics, bioavailability, metabolism and excretion of δ-veniferin in rats.  Acta Pharmaceutica Sinica B , 2016,6(3): 243-252.

Books

Honors & Awards