LU Duo
Principal Investigator
Lu Duo is interested in the structures of biomolecules that potentially can be targeted by drug molecules. Two major aspects are currently studied in his group: protein-protein interactions in transcription regulation and membrane proteins.
1. Oxygen impact on genome structure and chemistry. Acta Pharmaceutica Sinica, 2020, 55: 1744-1753.
2. A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity. Cancer Letters, 2020, 495:22-32.
3. DNA recognition patterns of the multi-zinc-finger protein CTCF: a mutagenesis study. Acta Pharmaceutica Sinica B, 2018, 8:900-908.
4. The Ikaros family of zinc-finger proteins. Acta Pharmaceutica Sinica B, 2016, 6: 513-521.
5. Epigenetic modification enzymes: catalytic mechanisms and inhibitors. Acta Pharmaceutica Sinica B, 2013, 3: 141-149.
6. C2H2 zinc-finger recognition of biomolecules. Acta Pharmaceutica Sinica, 2013, 48: 834-841.
