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LI Guang Principal Investigator
Professor

Department :

Department of Synthetic Medicinal Chemistry

Platform :

State Key Laboratory of Bioactive Substance and Function of Natural Medicines
Beijing Key Laboratory of Active Substances Discovery and Druggability Evaluation

Contact Details

Li Guang's group
guang.li@imm.ac.cn
Brief Introduction

Guang received his B.Sc in Applied chemistry from Southwest University in 2008, and his Ph.D. in organic chemistry from Institute of chemistry, Chinese Academy of Sciences (ICCAS) in 2013 under the direction of Professor Yian Shi. From 2013, He conducted his postdoctoral research at Tsinghua University, and later at École Polytechnique Fédérale de Lausanne(EPFL), Switzerland. He joined the faculty of IMM, CAMS&PUMS as an assistant professor in the summer of 2021. His research interest include total syntheses of natural products with structural complexity and medicinal chemistry based on the bioactive natural products.

Achievements

Papers

1. Unified Divergent Strategy towards the Total Synthesis of the Three Sub-classes of Hasubanan Alkaloids.  Nat. Commun . 2021. DOI: org/10.1038/s41467-020-20274-1.

2. Enantioselective Total Synthesis of (+)-Alstilobanine C, (+)-Undulifoline and (-)-Alpneumine H.  Angew. Chem. Int. Ed . 2021,  60 , 12392-12395.

3. Stereoselective Total Synthesis of Eburnane-Type Alkaloids Enabled by Conformation-Directed Cyclization and Rearrangement.  Angew. Chem. Int. Ed . 2019,  58 , 2870-2874.

4. Total synthesis of (±)-Calophyline A.  Angew. Chem. Int. Ed . 2016,  55 , 10483-10486. (Cover paper)

5. Indoxyl Based Strategy to Indolines and Indolenines.  Angew. Chem. Int. Ed. 2015.  54 . 12627-12631.

Books

Honors & Awards