HOU Qi
Principal Investigator
Hou Qi's research focuses on:
1. Anti-inflammatory immunopharmacology and its related new drug discovery;
2. New targets and mechanisms of inflammation regulation in asthma and COPD;
3. Drug screening for rheumatoid, rheumatoid and osteoarthritis;
4. Immunopathological mechanism of aplastic anemia and its drug discovery;
5. Screening of allergens from TCM based on antigen-immunomagnetic beads.
1. Comparative RNA‐Seq transcriptome analysis on pulmonary inflammation in a mouse model of asthma-COPD overlap syndrome. Frontiers in Cell and Developmental Biology. 2021，doi: 10.3389/fcell.2021.628957.
2. Syk-Targeted, a New 3-Arylbenzofuran Derivative EAPP-2 Blocks Airway Inflammation of Asthma–COPD Overlap in vivo and in vitro. Journal of Inflammation Research. 2021，14：2173-2185.
3. Brusatol Derivative - 34 Attenuates Allergic Airway Inflammation via Inhibition of the Syk Pathway. Frontiers in Pharmacology. 2021, doi: 10.3389/fphar.2021.587417.
4. Perilla Leaf Extract Attenuates Asthma Airway Inflammation by Blocking the Syk Pathway. Mediators of Inflammation. 2021，2021：6611219.
5. Multiple Components Rapidly Screened from Perilla Leaves Attenuate Asthma Airway Inflammation by Synergistic Targeting on Syk. Journal of Inflammation Research. 2020:13 897-911.
6. hondroprotective and anti-inflammatory effects of amurensin H by regulating TLR4/Syk/NF-κB signals. J Cell Mol Med. 2020;24:1958-1968
7. Amurensin H, a derivative from resveratrol, ameliorates lipopolysaccharide / cigarette smoke‐induced airway inflammation by blocking the Syk/NF-κB pathway. Frontiers in Pharmacology. 2019, 10: 1157.
8. Beneficial Effects of Qingzixiaoban Granule on Henoch–Sch¨onlein Purpura Nephritis Mice through Inhibiting Immune Complex Deposition and Th2 Immunodeviation. ECAM. 2019: 3050248.
9. Tamarixinin A alleviates joint destruction of rheumatoid arthritis by blockade of MAPK and NF-κB activation. Frontiers in Pharmacology. 2017, 8: 538.
10. Vam3, a Compound Derived from Vitis amurensis Rupr., Attenuated Colitis-Related Tumorigenesis by Inhibiting NF-kappa B Signaling Pathway. Frontiers in Pharmacology, 2016.9.13, 7.
11. 14, 15- Epoxyeicosatrienoic acid suppresses cigarette smoke condensate-induced inflammation in lung epithelial cells by inhibiting autophagy. AMERICAN Journal of Physiology-Lung Cellular And Molecular Physiology, 2016.11.1, 311(5): L970-L980.
12. Vam3 ameliorates total body irradiation-induced hematopoietic system injury partly by regulating the expression of Nrf2-targeted genes. Free Radical Biology and Medicine, 2016.12, 101: 455-464.
