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GUO Qinglan
Associate Professor

Department :

Department of Natural Medicinal Chemistry

Platform :

State Key Laboratory of Bioactive Substance and Function of Natural Medicines

Contact Details

Shi Jiangong's group
guonina@imm.ac.cn
Brief Introduction

Dr. Guo Qinglan received her Ph.D. degree in 2014 from the Institute of Materia Medica, Chinese Academy of Medicial Sciences & Peking Union Medical College, and then joined Shi Jiangong's group. She is currently an associate professor of medicinal chemistry in natural product chemistry and her interest focuses on minor and/or water-soluble constituents of commonly used traditional Chinese medicines. She has authored and/or co-authored 50+ scientific publications and was granted seven patents.

Achievements

Papers

1. Indole alkaloid glycosides with a 1ʹ-(phenyl)ethyl unit from  Isatis indigotica leaves.  Acta Pharm Sin B. 2020, 10(5): 895-902.

2. Structure, property, biogenesis, and activity of diterpenoid alkaloids containing a sulfonic acid group from  Aconitum carmichaelii .  Acta Pharm Sin B. 2020,10(10):1954-1965.

3. Aconicarmisulfonine A, a sulfonated C20-diterpenoid alkaloid from the lateral roots of  Aconitum carmichaelii.  Org. Lett. 2018: 20:816-819.

4. C19-Diterpenoid alkaloid arabinosides from an aqueous extract of the lateral root of  Aconitum carmichaelii and their analgesic activities.  Acta Pharm Sin B2018, 8(3): 409-419.

5. Sulfur-enriched alkaloids from the root of  Isatis indigotica.  Acta Pharm. Sin. B. 2018, 8(6): 933-943.

6. 4-Hydroxybenzyl-substituted amino acid derivatives from  Gastrodia elata.  Acta Pharm Sin B. 2015, 5(4): 350–357.

7. A minor diterpenoid with a new 6/5/7/3 fused-ring skeleton from  Euphorbia micractina.  Org. Lett. 2014, 16: 3950–3953.

8. Oxaspiroangelioic acids A-C with an unprecedented carbon skeleton from an aqueous extract of the  Angelica sinensis root head.  Chin. Chem. Lett.  2021, doi.org/10.1016/j.cclet.2021.03.004.

9. Gastrolatathioneine, an unusual ergothioneine derivative from an aqueous extract of ''Tian ma'': A natural product co-produced by plant and symbiotic fungus.  Chin. Chem. Lett.  2016, 27 (10):1577–1581.

10. Minor alkaloids from an aqueous extract of the hook-bearing stem of  Uncaria rhynchophylla.  J. Asian Nat. Prod. Res. 2021, 23: 513-526.

11. 4-Hydroxybenzyl-substituted glutathione derivatives from  Gastrodia elata.  J. Asian Nat. Prod. Res. 2015, 17(5): 439–454.

12.Insight into Medicinal Chemistry Behind Traditional Chinese Medicines:  p Hydroxybenzyl AlcoholDerived Dimers and Trimers from  Gastrodia elata.  Nat. Prod. Bioprospect. 2021, 11: 31-50.

Books

Honors & Awards