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GONG Ting
Associate Professor

Department :

Department of Biosynthesis of Natural Products

Platform :

State Key Laboratory of Bioactive Substance and Function of Natural Medicines
NHC Key Laboratory of Biosynthesis of Natural Products
CAMS Key Laboratory of Enzyme and Catalysis of Natural Drugs

Contact Details

Zhu Ping's group
gongting@imm.ac.cn
Brief Introduction

Educational background

09/2005-07/2010, Institute of Materia Medica, CAMS & PUMC, Ph.D. in medicinal chemistry

09/2001-07/2005, Shenyang Pharmaceutical University, B.S. in traditional Chinese pharmacology

Work experience

10/2016 - present, Associated research fellow, Institute of Materia Medica, CAMS

09/2016-08/2010, Assistant research fellow, Institute of Materia Medica, CAMS

Research interests

1.  Discovery of bioactive natural products from the microorganisms, such as marine microorganisms, or medicinal fungi, etc.

2.  Synthetic biology of scarce and natural medicines, recombinant enzymes of biocatalysis.

Achievements

Papers

1. Fed-batch high-cell-density fermentation strategies for  Pichia pastoris growth and production. Crit. Rev. Biotechnol., 2019, 39(2): 258-271.

2. Tetrocarcin Q, a New Spirotetronate with a Unique Glycosyl Group from a Marine-Derived Actinomycete  Micromonospora carbonacea LS276. Marine Drugs, 2018, 16, 74.

3. Chrysoxanthones A–C, Three New Xanthone–Chromanone Heterdimers from Sponge-Associated  Penicillium chrysogenum HLS111 Treated with Histone Deacetylase Inhibitor. Marine Drugs, 2018, 16, 357.

4. Improving 10-deacetylbaccatin III-10-β-Oacetyltransferase catalytic fitness for Taxol production. Nature Communications, 2017, 8: 15544.

5. Scaling-up fermentation of  Pichia pastoris to demonstration-scale using new methanol-feeding strategy and increased air pressure instead of pure oxygen supplement. Scientific Reports, 2016, 6: 18439.

6. A new analogue of echinomycin and a new cyclic dipeptide from a marine-derived  Streptomyces sp. LS298. Marine Drugs, 2015, 13(11): 6947-6961.

7. Two new monoterpenoid α-pyrones from a fungus  Nectria sp. HLS206 associated with the marine sponge  Gelliodes carnosa. J Asian Nat Prod Res., 2015, 17(6): 633-637.

8. Microbial transformation of oleanolic acid by  Trichothecium roseum. J Asian Nat Prod Res., 2014, 16(4): 383-386.

9. Two new isoflavone glycosides from the vine stem of  Millettia dielsiana. J Asian Nat Prod Res., 2014, 16 (2): 181.

10. A novel 3-arylcoumarin and three new 2-arylbenzofurans from  Mucuna birdwoodiana. Chemical & Pharmaceutical Bulletin, 2010, 41 (29): 254-256.

Books

Honors & Awards