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GONG Ningbo
Associate Professor

Department :

Research Center of Polymorphic Drugs

Platform :

Beijing Key Laboratory of Polymorphic Drugs

Contact Details

Lu Yang's group
gnb@imm.ac.cn
Brief Introduction

Education and working background

1990-1994: Hubei University of Traditional Chinese Medicine, bachelor

1998-2001: China Peking Union Medical College, master

2005-2008: Peking Union Medical College, PhD

09/1994-07/2001: Beijing Medical College, assistant

09/2001-03/2005: Yanjing Medical College, Capital Medical University, lecturer

09/2008-present: Institute of Materia Medica, Chinese Academy of Medical Sciences, associate professor

Research field

1. Three-dimensional structure analysis of natural products, drugs, and API;

2. Polymorphic analysis of drugs and API;

3. Development of reference materials;

4. Research on new technologies and methods of analytical chemistry.

Achievements

Papers

1. Salt or/and cocrystal? The case of the antidepressant drug venlafaxine.  CrystEngComm , 2021, 23:2665-2672

2. Venlafaxine Caffeic Acid Salt: Synthesis, Structural Characterization, and Hypoglycemic Effect Analysis.  ACS Omega, 2021, 6, 21:13895-13903

3. Versatile salts as a strategy to modify the biopharmaceutical properties of venlafaxine and potential hypoglycemic effect study. CRYSTAL GROWTH & DESIGN, 2020, 20:3131-3139.

4. Control over Polymorph Formation of Polydatin in Binary Solvent System and Structural Characterization. Journal of Pharmaceutical and Biomedical Analysis, 2020, 189:113260.

5. Polymorphs and Transformations of the Solid Forms of Organic Salts of 5-Sulfosalicylic Acid and Isonicotinamide. CRYSTAL GROWTH & DESIGN, 2020, 20, 12:7606–7614

6. Crystal structures, dissolution and pharmacokinetic study on a novel phosphodiesterase-4 inhibitor chlorbipram cocrystals. International Journal of Pharmaceutics, 2020, 576: 118984.

7. Structure, characterization, solubility and stability of podophyllotoxin Polymorphs. Journal of Molecular Structure, 2019, 1195:323-330.

8. Salt formation of two BCS II drugs (indomethacin and naproxen) with (1R, 2R)-1,2-diphenylethylenediamine: Crystal structures, solubility and thermodynamics analysis.  Journal of Molecular Structure, 2019, 1185:281-289.

9. Screening, preparation and characterization of diosgenin versatile solvates.  Steroids, 2019,143:18-24.

10. Carbamazepine cocrystals with several aromatic carboxylic acids in different stoichiometries: Structures and solid state characterization.  Journal of Molecular Structure, 2018,1168:145-152.

Books

1. Experimental pharmacology, Du G.H.(..Gong Ningbo..)  Higher Education Press, 2021, Pages 233-239. Print ISBN: 978-7-04-054780-1.

2. Polymorphs drugs, Lu Y., and Du G.H. (..Gong Ningbo..)  People's Medical Publishing House, 2019, Pages 310-372. Print ISBN: 978-7-117-28034-1.

3. Natural Small Molecule Drugs from Plants,Du G.H. (..Gong Ningbo..) People's Medical Publishing House, 2018, Pages 152-154, 194-196. Print ISBN: 978-7-117-24870-9/R.24871.

4. Natural Small Molecule Drugs from Plants,Du G.H. (..Gong Ningbo..) Springer, 2018, Pages 353-356, 427-431. Print ISBN: 978-7-117-29101-9.

5. A review of ancient and modern research on Chinese medicinal materials (poisons), Du G.H. (..Gong Ningbo..). China Medical Science and Technology Press, 2018, Pages 112-121. Print ISBN: 978-7-5214-0668-9.

Honors & Awards

1. 2016. National Science and Technology Progress Award, second prize, China.

2. 2014. Beijing Science and Technology Award, first prize, China.