FENG Wenhua
Principal Investigator
Feng Wenhua is a researcher and master tutor at the Institute of Materia Medica, Chinese Academy of Medical Sciences, and a member of the Veterinary Drug Evaluation Center of the Ministry of Agriculture. He has many years of experience in drug research, development, and review, and he is proficient in drug regulations. Focusing on the drug synthesis process, many of his processes have successfully challenged foreign process patents. At the same time, he provides products and technical support for domestic institutions and enterprises in new drug research. He undertook some major scientific research projects supported by the Ministry of Science and Technology and Technology, and international project from the Clinton Foundation. He has developed and marketed some new drugs such as donepezil hydrochloride, tirofiban hydrochloride, loratadine, etc.
1. A novel method for preparing Eligulstat through chiral resolution. Bioorganic & Medicinal Chemistry Letters 2020, 30(16): 127209-127212.
2. A Practical and Total Synthesis of Pasireotide: Synthesis of Cyclic Hexapeptide via a Three-Component Condensation. Molecules 2019, 24(11): 2185-2197.
3. Ag/Pyridine Co-Mediated Oxidative Arylthiocyanation of Activated Alkenes. Molecules 2018, 23(10): 2727.
4. N,O-bis(trimethylsilyl)acetamide/N-hydroxysuccinimide ester (BSA/NHS) as coupling condition for dipeptide synthesis. Chinese Chemical Letters 2016, 27(03): 357-360.
5. Facile catalyst-free synthesis of 2-vinylquinolines via a direct deamination reaction occurring during Mannich synthesis. RSC Advances 2015, 5(120): 99095-99098.
6. A highly efficient way to recycle inactive stereoisomers of Bedaquiline into two previous intermediates via base-catalyzed Csp3-Csp3 bond cleavage. Chinese Chemical Letters 2015, 26(06): 790-792.
