CUI Huaqing
Principal Investigator
Dr. Cui Huaqing obtained his PhD degree from the University of Heidelberg in 2010. His research experiences include a 3-year postdoctoral research experience at the University of Minnesota, Minneapolis, a student exchange experience at the University of Dundee, UK and Institute of Parasitology and Biomedicine, CSIC, Spain. Dr. Cui joined IMM in 2013 and started his independent research in 2017. His research mainstay is innovative drug discovery, but he also worked to develop interesting IVD products.
1. Determining essential requirements for fluorophore selection in various fluorescent applications taking advantage of diverse structure fluorescence information of chromone derivatives. J. Med. Chem., 2021; 64(2):1001-1017.
2. Synthesis and evaluation of benzenesulfonic acid derivatives as human neutrophil elastase (hNE) inhibitors. Med. Chem. Res., 2021, 30: 387-398.
3. Taking advantage of the aromatisation of 7-diethylamino-4-methyl-3, 4-dihydrocoumarin to fluorescently sense superoxide anion. ChemComm., 2020, 56 (68): 9827-9829.
4. Precisely evaluation in vivo target efficacy of anti-tumour agents via an immunofluorescence and EdU labelling strategy. Front Pharmacol. , 2018, 9:812.
5. A Suzuki-Miyaura Protocol for Labelling Proliferating Cells Containing Incorporated BrdU. Analyst , 2018, 143(5), 1224-33.
6. Fragment based structural simplification of bedaquiline: the discovery of 3-(4-(N, N-dimethylaminomethyl)phenyl)-quinoline derived anti-tubercular lead compounds. ChemMedChem., 2017,12 (2):106-119.
7. A high-resolution method to assess cell multinucleation with cytoplasm-localized fluorescent probes. Analyst., 2016, 141 (13), 4010-3.
8. Development of 3-alkyl-6-methoxy-7-hydroxychromones (AMHCs) from natural isoflavones, a new class of fluorescent scaffolds for biological imaging. ChemComm., 2015, 51 (5): 881-5.
9. Discovery of potent and selective Sirtuin 2 (SIRT2) inhibitors using a fragment-based approach. J. Med. Chem., 2014, 57:8340-8357;
10. Synthesis and evaluation of α-thymidine analogues as novel antimalarials. J. Med. Chem., 2012, 55 (24): 10948-10957.
