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CHEN Dawei
Associate Professor

Department :

Department of Biosynthesis of Natural Products

Platform :

NHC Key Laboratory of Natural Drug Biosynthesis
CAMS Key Laboratory of Enzymes and Natural Drug Biocatalysis

Contact Details

Dai Jungui's group
chendawei@imm.ac.cn
Brief Introduction

Chen Dawei graduated from Peking Union Medical College with Ph. D degree in 2016. Then he joined the Institute of Materia Medica, Chinese Academy of Medical Sciences. His research interest focused on the biosynthesis of medicinal natural glycosides. As the first author, he has published 12 SCI papers in famous international journals, such as Angewandte Chemie International Edition, ACS Catalysis, Organic Letters, etc. In 2018, he won the honor of "Excellent Doctoral Dissertation of Peking Union Medical College". In 2016, he was awarded the title of "Outstanding Graduate of Beijing Normal University".

Achievements

Papers

1. Biocatalytic application of a membrane-bound coumarin C-glucosyltransferase in the synthesis of coumarin and benzofuran C-glucosides. Advanced Synthesis & Catalysis, 2021, DOI: 10.1002/adsc.202100041.

2. Probing and engineering key residues for bis-C-glycosylation and promiscuity of a C-glycosyltransferase. ACS Catalysis, 2018, 8 (6):4917-4927.

3. Biocatalytic C-glucosylation of coumarins using an engineered C-glycosyltransferase. Organic Letters, 2018, 20 (6):1634–1637.

4. Enzymatic synthesis of acylphloroglucinol 3-C-glucosides from 2-O-glucosides using a C-glycosyltransferase from Mangifera indica. Chemistry-A European Journal, 2016, 22 (17):5873–5877.

5. Probing the catalytic promiscuity of a regio- and stereo-specific C-glycosyltransferase from Mangifera indica. Angewandte Chemie International Edition, 2015, 54 (43):12678-12682.

Books

Honors & Awards