王宝莲，男，博士，副研究员，硕士生导师。
2009年-至今于中国医学科学院药物研究所工作，先后任助理研究员、副研究员，兼任中国药理学会药物代谢专业委员会青年委员，2010年-2011年作为访问学者于美国纽约州卫生署研修。
工作期间参与完成多项化学Ⅰ类创新药物临床前药代动力学研究工作，主持或参与国家自然科学基金、北京市科委重点基金、国家科技部重大新药创制专项、国家“十一五”“十二五”“十三五”重大专项等多项课题，发表学术研究论文30余篇。

1. 先导物药代特性早期评价
2. 新药临床前药代动力学及PK/PD研究
3. 药物代谢酶和转运蛋白的调控及分子机制
4. 中药及天然产物药代动力学研究

1. Jianwei Jiang, Yuke Liu, Xiao Liu, Dongfeng Zhang, Haihong Huang, Baolian Wang*, Li Sheng*, Yan Li. Simultaneous determination of a novel oxazolidinone anti-tuberculosis OTB-658 and its metabolites in monkey blood by LC-MS/MS[J]. Journal of Chromatography B, 2021,1167: 122552
2. Minwan Hu, Yang Li, Feng You, Jie Bai, Xiaoqing Fan, Shengyu Zhao, Yanhong Sun, Baolian Wang*, Jinping Hu*, Yan Li. Comparison and identification of metabolic profiling of bicyclol in rats, dogs and humans in vitro and in vivo[J]. European Journal of Pharmaceutical Sciences, 2020, 154: 105518.
3. Xiong Chen, Song Wu, Jinlan Zhang, Dongmei Wang, Baolian Wang*. Polymorphic study and pharmacokinetic evaluation of hypolipidemic candidate IMM-H007. Chinese Journal of Pharmaceuticals, 2020, 51(8): 1029-1035
4. Rui Wang, Baolian Wang*, Yan Li*. Pharmacokinetics of IMM-H007 after oral administration in Rhesus monkey using HPLC-MS/MS analysis. Acta Pharmaceutica Sinica, 2018, 53(7): 1156-1161.
5. Fen Yang1, Baolian Wang1, Zhihao Liu, Xuejun Xia, Weijun Wang, Dali Yin, Li Sheng, Yan Li. Prediction of a therapeutic dose for Buagafuran, a potent anxiolytic agent by physiologically based pharmacokinetic/pharmacodynamic modeling starting from pharmacokinetics in rats and human.[J] Frontiers in Pharmacology, 2017, 8: 683. doi: 10.3389/fphar.2017.00683.
6. Shuang Yang, Jiaqi Mi, Zhihao Liu, Baolian Wang*, Xuejun Xia, Renyun Wang, Yuling Liu, Yan Li. Pharmacokinetics, tissue distribution and elimination of three active alkaloids in rats after oral administration of the effective fraction of alkaloids from Ramulus Mori, an innovative hypoglycemic agent[J]. Molecules, 2017, 22(10), 1616; doi:10.3390/molecules22101616
7. Yufei Jia, Baolian Wang, Xiangmeng Wu, Sheng Li, Jinping Hu, Dongmei Wang，Haibo Zhu, Yan Li. Simultaneous quantification of 2,3,5-tri-O- acetyl-N6-(3-hydroxylaniline)adenosine and its principal metabolites in hamster blood by LC–MS/MS and its application in pharmacokinetics study[J]. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 2016, 1022：46-53.
8. Baolian Wang, Zhihao Liu, Dan Li, Shuang Yang, Jinping Hu, Hui Chen, Li Sheng, Yan Li. Application of physiologically based pharmacokinetic modeling in the prediction of pharmacokinetics of bicyclol controlled-release formulation in human[J]. European Journal of Pharmaceutical Sciences, 2015, 77: 265-272.
9. Baolian Wang, Shuang Yang, Li Sheng, Yan Li. Simultaneous quantification of curdione, furanodiene and germacrone in rabbit plasma using liquid chromatography–tandem mass spectrometry and its application to a pharmacokinetic study[J]. Biomedical Chromatography, 2015,29（9）:1393-1398.
10. Shuang Yang, Baolian Wang, Xuejun Xia, Xue Li, Renyun Wang, Li Sheng, Dan Li, Yuling Liu, Yan Li. Simultaneous quantification of three active alkaloids from atraditional Chinese medicine Ramulus Mori (Sangzhi) in rat plasma using liquid chromatography-tandem mass spectrometry[J]. Journal of Pharmaceutical and Biomedical Analysis，2015, 109：177-183.
11. Baolian Wang, Li Sheng, Yan Li. Simultaneous determination of telmisartan and amlodipine in dog plasma by LC-MS-MS[J]. Journal of Chromatographyic Science，2015, 53（10）：1708-1713.
12. Baolian Wang, ShuangYang, JinpingHu, YanLi. Multifaceted interaction of the traditional Chinese medicinal herb Schisandra chinensis with cytochrome P450-mediated drug metabolism in rats[J]. Journal of Ethnopharmacology, 2014, 155: 1473–1482.
13. Baolian Wang, Jinping Hu, Li Sheng, Yan Li. Chemical-Pharmacokinetic (PK)- Pharmacodynamic (PD) Fingerprints Study of Schisandra chinensis Alcoholic Extract. Acta Pharmaceutica Sinica. 2013, 48(5): 734-740.