2015年毕业于中国医学科学院药物研究所，获理学博士学位，导师戴均贵研究员，同年留所工作。2018年9月获聘为副研究员，硕士生导师。获得2020年中国药学会青年药学论坛优秀论文一等奖、2020年中国医学科学院药物研究所“梁周黄于刘青年科技奖”三等奖、北京市优秀毕业生以及国家奖学金等荣誉。作为负责人承担国家自然科学基金面上基金项目、青年基金项目等；作为子课题负责人或骨干人员参与了中国医学科学院医学与健康科技创新工程、国家“十三五”重大新药创制专项等课题。以第一/共同第一/共同通讯作者发表SCI论文20余篇，包括Nature Communications、Angewandte Chemie International Edition、Organic Letters等国际期刊论文。申请专利10余项，其中授权3项。

研究方向为药用天然产物的生物合成与酶法结构修饰。主要研究内容为
1. 解析复杂药用天然产物生物合成途径中的新颖关键酶及其催化机制；
2. 利用分子生物学手段，拓宽酶的底物谱，开发工具酶，应用于目标分子的高效酶法合成；
3. 构建人工生物合成途径，高效生产活性天然及非天然药物，解决创新药物的来源问题。

1. Ruiqi Yan#, Binghan Xie#, Kebo Xie#*, Qi Liu#, Songyang Sui, Shuqi Wang, Dawei Chen, Jimei Liu, Ridao Chen, Jungui Dai* & Lin Yang*. Unravelling and reconstructing the biosynthetic pathway of bergenin. Nature Communications, 2024, 15, 3539. (IF 16.6，共同第一兼通讯作者)
2. Changkang Li#, Xinxin Yin#, Shuai Wang, Songyang Sui, Jimei Liu, Xincheng Sun, Jinming Di, Ridao Chen, Dawei Chen, Yaotian Han, Kebo Xie*, Jungui Dai*. A Cytochrome P450 Enzyme Catalyses Oxetane Ring Formation in Paclitaxel Biosynthesis. Angewandte Chemie International Edition, 2024, e202407070. (IF 16.8，共同通讯作者)
3. Kebo Xie#*, Xiaolin Zhang#, Songyang Sui, Fei Ye* and Jungui Dai*. Exploring and applying the substrate promiscuity of a C-glycosyltransferase in the chemo-enzymatic synthesis of bioactive C-glycosides. Nature Communications, 2020, 11, 1-12 (IF 12.1，共同第一兼通讯作者).
4. Kebo Xie#*, Qian Zhang#, Fei Ye, Jungui Dai*. A multi-enzymatic cascade reaction for the synthesis of bioactive C-oligosaccharides. Chinese Chemical Letters 2024, 35, 109028. (IF 9.1，共同第一兼通讯作者).
5. Kebo Xie, Ridao Chen, Jianhua Li, Ruishan Wang, Dawei Chen, Xiaoxiang Dou, and Jungui Dai*, Exploring the catalytic promiscuity of a new glycosyltransferase from Carthamus tinctorius, Organic Letters, 2014, 16, 4874-4877. (IF 6.56，第一作者)
6. Kebo Xie, Ridao Chen, Dawei Chen, Jianhua Li, Ruishang Wang, Lin Yang and Jungui Dai*, Enzymatic N-Glycosylation of Diverse Arylamine Aglycones by a Promiscuous Glycosyltransferase from Carthamus tinctorius. Advanced Synthesis & Catalysis, 2017, 359, 603‒608. (IF 5.45，第一作者)
7. Songyang Sui#, Kebo Xie#, Ruimingqian Guo, Jungui Dai*, and Lin Yang*. Molecular characterization of a stereoselective and promiscuous flavanone 3-hydroxylase from Carthamus tinctorius L. Journal of Agricultural and Food Chemistry, 2023, 71, 1679-1689. (IF 6.1, 共同第一作者)
8. Tian Yue, Ridao Chen, Dawei Chen, Jimei Liu, Kebo Xie* and Jungui Dai*, Enzymatic Synthesis of Bioactive O-Glucuronides Using Plant Glucuronosyltransferases, Journal of Agricultural and Food Chemistry, 2019, 67, 6275-6284. (共同通讯作者)
9. Yujiao Zhang#, Kebo Xie#, Aijing Liu, Ridao Chen, Dawei Chen, Lin Yang, Jungui Dai* Enzymatic biosynthesis of benzylisoquinoline alkaloid glycosides via promiscuous glycosyltransferases from Carthamus tinctorius. Chinese Chemical Letters, 2019, 30, 443-446. (共同第一作者)
10. Kebo Xie#, Xiaoxiang Dou#, Ridao Chen, Dawei Chen, Cheng Fang, Zhiyan Xiao and Jungui Dai*, Molecular Characterization and Phylogenetic Analysis of Two Novel Fungal Phenolic UDP-Glycosyltransferases from Absidia coerulea and Rhizopus japonicus. Applied and Environmental Microbiology, 2017, AEM-03103. (共同第一作者)

1. 解可波, 戴均贵, 陈日道, 陈大伟, 刘继梅. 一种芦荟C-糖基转移酶序列及其在催化C-糖基化中的应用，授权专利号：201811485713.6
2. 解可波, 叶菲, 戴均贵, 张晓琳, 尹震, 陈日道, 陈大伟, 刘继梅. 一类碳糖苷类化合物及其制备和用途，授权专利号：201910521052.6
3. 陈乃宏, 李燕, 戴均贵, 宋修云, 盛莉, 乐田, 楚世峰, 张梓倩, 解可波, 谭圳. 一种香豆素衍生物代谢产物的制备及其在防治脑缺血和阿尔茨海默病中的应用. 授权专利号：ZL201810317196.5