主持多项国家自然科学基金面上项目、青年基金、协和青年基金等项目。作为课题骨干先后参与国家自然基金重点项目、“十三五”重大专项等重大研究课题。现任北京药学会天然药物专业委员会委员，《中国中药杂志》编委。
1. 工作经历
2021.10至今 中国医学科学院&北京协和医学院，药物研究所，研究员；
2014.10-2021.9 中国医学科学院&北京协和医学院，药物研究所，副研究员；
2009.8-2014.9 中国医学科学院&北京协和医学院，药物研究所，助理研究员；
2. 教育背景
2006.8-2009.7 中国医学科学院&北京协和医学院，药物研究所，药物化学博士；
2003.8-2006.7 天津中医药大学，中药化学硕士；
1999.8-2003.7 天津中医药大学，中药学学士。

1. 功能导向的活性天然产物的发现及修饰：针对疼痛、癌症等重大疾病需求，寻找新的活性先导化合物，以及揭示天然产物新的功能。
2. 活性天然产物的靶标鉴定与作用机制研究：通过化学生物学技术研究活性天然产物分子的作用靶标，揭示天然产物干预疾病发生、发展过程的作用机制。

1. Keliang Chen#, Tao Wang#, Yong Li#, Jun Wu#, Cheng-Xiao Zhao, Sheng Liu, Fengrun Sun, Yehong Fang, Jiahuan Hu, Jinping Hu, Chong-Jing Zhang*, Haibo Yu*, Chao Ma*, Shi-Shan Yu*. Rhodojaponin VI indirectly targets Cav2.2 channels via N-ethylmaleimide-sensitive fusion protein to alleviate neuropathic pain. Acta Pharmaceutica Sinica B, 2023, 13(3): 1326-1336.
2. Yuxun Zhu, Shangyi Wang, Zhaoxin Zhang, Huanping Zhang, Lisha Chai, Guosheng Liu, Chengshuo Yang, Haijing Zhang, Lianqiu Wu*, Yong Li*. Pseudoamaolides A-O, anti-inflammatory triterpene spiroketal lactones from seeds of Pseudolarix amabilis. Bioorganic Chemistry, 2022, 129, 106180.
3. Guo-Zhu Su#, Shang-Yi Wang#, Xiu-Ying Yang, Zora Dajić Stevanović, Na Li, Nikola Tanić, Nebojsa Arsenijevic, Shi-Shan Yu*, Yong Li*. Dihydroflavonoid glycosides from Viscum album and their inhibitory effects on hepatic lipid accumulation and target identification. Phytochemistry, 2022, 204, 113458.
4. Hai-Yan Cao#, Cheng Yi, Sen-Feng Sun, Yong Li*, and Yun-Bao Liu*. Anti-inflammatory Dimeric Tetrahydroxanthones from an Endophytic Muyocopron laterale. J. Nat. Prod. 2022, 85, 1, 148−161.
5. Shu-Meng Xiao, Yun-Bao Liu, Jing Qu, Shuang-Gang Ma, Yong Li*, Shi-Shan Yu*. Analgesic grayanoids from Craibiodendron henryi. Tetrahedron, 2022, 120, 132892.
6. Antinociceptive grayanane-derived diterpenoids from flowers of Rhododendron mole. Yong Li, Yuxun Zhu, Zhaoxin Zhang, Li Li, Yunbao Liu, Jing Qu, Shuanggang Ma, ShishanYu*. Acta Pharmaceutica Sinica B. 2020, 10(6), 1073-1082.
7. New triterpenoids from the roots of Rhododendron molle as positive modulators of GABAA receptors. Huan-Ping Zhang, Yu-Xun Zhu, Zhao-Xin Zhang, Li-Sha Chai, Yun-Bao Liu, Hai-Bo Yu, Yong Li*. Tetrahedron, 2020, 76(37), 131455.
8. Micranthuosides I and II, twonovel 1,10-secograyanane diterpenoids and their antinociceptive analogues from the leaves and twigs of Rhododendron micranthum. Yuxun Zhu, Huimin Yan, Xiaojing Wang, Zhaoxin Zhang, Huanping Zhang, Lisha Chai, Li Li, Jing Qu, and Yong Li*. RSC Adv., 2019, 9, 18439.
9. New lignans, sesquiterpenes and other constituents from twigs and leaves of Rhododendron micranthum. Zhaoxin Zhang, Huimin Yan, Yuxun Zhu, Huanping Zhang, Lisha Chai, Li Li, Xiaojing Wang, Yunbao Liu, Yong Li*. Fitoterapia, 2019, 135, 15-21.
10. A new ascorbic acid derivative and two new terpenoids from the leaves and twigs of Rhododendron decorum. Yu-Xun Zhu, Zhao-Xin Zhang, Huan-Ping Zhang, Li-Sha Chai, Li Li, Shuang-Gang Ma & Yong Li*. J. Asian Nat. Prod. Res., 2019, 21, 579-586.
11. Antinociceptive Diterpenoids from the Leaves and Twigs of Rhododendron decorum. Yu-Xun Zhu, Zhao-Xin Zhang, Hui-Min Yan, Di Lu, Huan-Ping Zhang, Li Li, Yun-Bao Liu, and Yong Li*. J. Nat. Prod. 2018, 81, 1183-1192.
12. Diterpenoids from the fruits of Rhododendron molle, potent analgesics for acute pain. Yong Li, Yu-Xun Zhu, Zhao-Xin Zhang, Yang-Lan Liu, Yun-bao Liu, Jing Qu, Shuang-Gang Ma, Xiao-Jing Wang, Shi-Shan Yu*. Tetrahedron, 2018, 74, 693-699.
13. Rhodomollins A and B, two Diterpenoids with an Unprecedented Backbone from the Fruits of Rhododendron molle. Yong Li, Yun-Bao Liu, Hui-Min Yan, Yang-Lan Liu, Yu-HuanLi, Hai-Ning Lv, Shuang-Gang Ma, Jing Qu, Shi-Shan Yu*. Scientific Reports. 2016,6, 36752.
14. Antinociceptive Grayanoids from the Roots of Rhododendron molle. Yong Li, Yun-Bao Liu, Jian-Jun Zhang, Yang Liu, Shuang-Gang Ma, Jing Qu, Hai-Ning Lv, Shi-Shan Yu*. J. Nat. Prod. 2015, 78, 2887−2895
15. Mollanol A, a Diterpenoid with a New C-Nor-D-homo grayanane Skeleton from the Fruits of Rhododendron molle. Yong Li, Yun-Bao Liu, Yang-Lan Liu, Chen Wang, Lian-Qiu Wu, Li Li, Shuang-Gang Ma, Jing Qu, Shi-Shan Yu*. Org. Lett. 2014, 16, 4320-4323
16. Mollolide A, a Diterpenoid with a New 1,10:2,3-Disecograyanane Skeleton from the Roots of Rhododendron molle. Yong Li, Yun-Bao Liu, Jian-Jun Zhang, Yu-Huan Li, Jian-Dong Jiang, Shi-Shan Yu,* Shuang-Gang Ma, Jing Qu, Hai-Ning Lv. Org. Lett. 2013, 15,3074-3077
17. Grayanoids from the Ericaceae family: structures, biological activities and mechanism of action. Yong Li, Yun-Bao Liu , Shi-Shan Yu*. Phytochem.Rev. 2013, 77, 375-381
18. Cytotoxic cardenolides from the stems of Periploca forrestii. Yong Li, Yun-Bao Liu, Shi-Shan Yu*, Xiao-Guang Chen, Xian-Fu Wu, Shuang-Gang Ma, Jing Qu, You-Cai Hu, Jing Liu, Hai-Ning Lv. Steroids, 2012, 77, 375-381
19. Identification of cardiac glycosides infractions from Periploca forrestii by high-performance liquid chromatography/diode-array detection/electrospray ionization multi-stage tandem mass spectrometry and liquid chromatography/ nuclear magnetic resonance. Yong Li, Xianfu Wu, Jianbei Li, Yinghong Wang, Shishan Yu*, Haining Lv, Jing Qu, Zeper Abliz, Jing Liu, Yuanyan Liu, Dan Du. J. Chromatogr. B. 2010,878, 381– 390

1. 人工熊胆及其制备方法。庾石山，王晓良，李勇，屈晶，马双刚，刘云宝，王玲，徐少峰，冯楠，李江，徐孝先，张和平，郭经。授权公告日：2023-2-16。
2. 3-酰氧基取代右旋去氧娃儿藤宁衍生物、其制法和药物组合物与用途。庾石山，陈晓光，吕海宁，李超，徐嵩，刘云宝，马双刚，李勇。授权日：2019-01-01。
3. 抗柯萨奇病毒的二萜酸及其制法和其药物组合物与用途（中国）。庾石山，蒋建东，张贵杰，李玉环，屈晶，马双刚，刘云宝，李勇。授权日：2016-12-14。
4. 金钱松三萜内酯及其制法、药物组合物与用途。李勇，吴练秋，张海婧，朱裕勋，王雨菲。申请日：2020-2-4, 中国, 202010080047.9。
5. 一种角蛋白BD-15、制法和其药物组合物与用途。庾石山，王晓良，李勇，屈晶，蔡杰，徐少峰，刘云宝，张咪。申请日：2019-10-28, 中国, 201911028705.3。
6. 一种角蛋白BD-17、制法和其药物组合物与用途。庾石山，王晓良，李勇，苏国柱，李密，李江，徐少峰，张咪。申请日：2019-10-28, 中国, 201911028749.6。

1. 2020年，有毒中草药活性成分研究与质量安全标准制定及应用。庾石山，张东明，张聿梅，陈晓光，李勇，马双刚，刘云宝，屈 晶，侯琦，张丹。北京市科学技术一等奖。
2. 2013年，若干重要中草药中微量活性物质的研究。庾石山，石建功，张东明，于德泉，陈晓光，张建军，王珂，申竹芳，马双刚，林生，徐嵩，李勇，屈晶，吕海宁，李创军。北京市科学技术一等奖。
3. 2013年，中草药微量活性物质获取关键技术研究及其应用。庾石山，石建功，张东明，于德泉，陈晓光，张建军，王珂，申竹芳，马双刚，林生，徐嵩，李勇，屈晶，吕海宁，李创军。教育部科学技术进步二等奖。